Korean J Hematol 1997; 32(3):
Published online September 30, 1997
© The Korean Society of Hematology
유전분증이 동반된 비전형적 임상경과의 신증후성 출혈열 1례
이정은, 도영록, 김상일, 이원식, 송홍석
계명의대 내과학교실 및 유전의학연구소
A Case of Unusual Clinical Course in Patient with Hemorrhagic Fever with Renal Syndrome Associated with Secondary Amyloidosis
Hemorrhagic fever with renal syndrome(HFRS) is a symptom complex of fever, chill, myalgia, hemorrhagic diathesis and acute renal failure. We experienced a case of
non-oliguric HFRS associated severe thrombocytopenia. Peripheral blood smear showed large atypical lymphocytosis and hemophagocytic histiocytes on bone marrow aspiration.
Hantaan virus antibody titer was 1:5,120. Congo-red stain after potassium permanganate treatment of bone marrow biopsy revealed yellow-green birefringence and
immunohistochemistry for AA amyloid antibody showed weak positive staining in the stroma of the bone marrow.
Herein, we report a case of unusual HFRS associated with secondary amyloidosis and review the literature.
Keywords Hemorrhagic fever with renal syndrome; Amyloidosis;
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Korean J Hematol 1997; 32(3): 440-445
Published online September 30, 1997
Copyright © The Korean Society of Hematology.
유전분증이 동반된 비전형적 임상경과의 신증후성 출혈열 1례
이정은, 도영록, 김상일, 이원식, 송홍석
계명의대 내과학교실 및 유전의학연구소
A Case of Unusual Clinical Course in Patient with Hemorrhagic Fever with Renal Syndrome Associated with Secondary Amyloidosis
Jeong Eun Lee, Young Rok Do, Sang , Kim, Won Sig Lee, Hong Suk Song
Department of Internal Medicine and Institute of Medical Cytogenetics, Keimyung University, School of Medicine, Taegu, Korea
Abstract
Hemorrhagic fever with renal syndrome(HFRS) is a symptom complex of fever, chill, myalgia, hemorrhagic diathesis and acute renal failure. We experienced a case of
non-oliguric HFRS associated severe thrombocytopenia. Peripheral blood smear showed large atypical lymphocytosis and hemophagocytic histiocytes on bone marrow aspiration.
Hantaan virus antibody titer was 1:5,120. Congo-red stain after potassium permanganate treatment of bone marrow biopsy revealed yellow-green birefringence and
immunohistochemistry for AA amyloid antibody showed weak positive staining in the stroma of the bone marrow.
Herein, we report a case of unusual HFRS associated with secondary amyloidosis and review the literature.
Keywords: Hemorrhagic fever with renal syndrome, Amyloidosis,
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