Representative immuno-histochemical staining images of various type of diffuse large B-cell lymphomas.
Abbreviations: ABC, activated B-cell type; DLBCL, diffuse large B-cell lymphoma; GCB, germinal center B-cell type; EBV DLBCL, EBV-positive diffuse large B-cell lymphoma.|@|~(^,^)~|@|Representative images of immunohistochemical staining of small/low grade B-cell lymphomas. Tumor cells are positive for CD10 and Bcl-2 in follicular lymphoma, positive for CD5 and CD23 in chronic lymphocytic leukemia/small lymphocytic lymphoma, positive for cyclin D-1 and SOX11 in mantle cell lymphoma.
Abbreviation: CLL/SLL, chronic lymphocytic leukemia/small lymphocytic lymphoma.|@|~(^,^)~|@|Representative images of immunohistochemical staining of T/NK-cell lymphomas. In ALK-positive anaplastic large cell lymphoma, tumor cells are negative for CD3, and positive for CD30 and ALK. In angioimmunoblastic T-cell lymphoma, CD3 and CD20 shows mixed pattern of T- and B-cells. CD21 stain shows expanded follicular dendritic cell meshwork. EBV ISH is positive in scattered large B-cells. In extranodal NK/T-cell lymphoma, EBV positive cells are positive for CD3 and negative for CD79a in double stains.
Abbreviations: AITL, angioimmuno-blastic T-cell lymphoma; ALCL, ana-plastic large cell lymphoma; ENKTL, extranodal NK/T-cell lymphoma.|@|~(^,^)~|@|Representative images of immunohistochemical staining of precursor lymphomas. In T-lympho-blastic leukemia/lymphoma, tumor cells are positive for CD3, CD99 and TdT. In B-lymphoblastic leukemia/ lymphoma, tumor cells are negative for CD20, positive for CD79a and TdT.|@|~(^,^)~|@|Representative immunohistochemical staining images of Hodgkin lymphomas. In classic Hodgkin lymphoma, tumor cells are positive for CD30 and CD15. CD20 is negative and PAX5 is weak positive in large tumor cells. In nodular lymphocyte predominant Hodgkin lymphoma, tumor cells are positive for CD20 and Oct-2. CD30 is negative in tumor cells. CD3 stain shows peritumoral rosette-like T-cells.
Abbreviation: NLPHL, nodular lymphocyte predominant Hodgkin lymphoma.

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