Korean J Hematol 1995; 30(2):
Published online June 30, 1995
© The Korean Society of Hematology
자가면역 용혈성빈혈을 동반한 악성빈혈 1례
한지숙, 박준오, 이석, 정소영, 이승태, 민유홍, 고윤웅, 손창학
연세대학교 의과대학 내과학교실,
인제대학교 의과대학 부산백병원 내과학교실
A Case of Pernicious Anemia with Autoimmune Hemolytic Anemia
Pernicious anemia appears to be autoimmune in origin. Autoantibodies such as
anti-parietal cell antibody and anti-intrinsic factor antibody are found in about 90% and
70% of patients, respectively. It is commonly associated with autoimmune disorders of
several organ systems, but rarely with autoimmune hemolytic anemia. When pernicious
anemia and autoimmune hemolytic anemia occurs simultaneously, some diagnostic and
therapeutic difficulties exist.
We experienced a case of pernicious anemia associated with autoimmune hemolytic anemia. The patient was recovered by replacement of vitamin Bl2 and steroid therapy.
Keywords Pemicious anemia, Autoimmune hemolytic anemia
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Korean J Hematol 1995; 30(2): 315-320
Published online June 30, 1995
Copyright © The Korean Society of Hematology.
자가면역 용혈성빈혈을 동반한 악성빈혈 1례
한지숙, 박준오, 이석, 정소영, 이승태, 민유홍, 고윤웅, 손창학
연세대학교 의과대학 내과학교실,
인제대학교 의과대학 부산백병원 내과학교실
A Case of Pernicious Anemia with Autoimmune Hemolytic Anemia
Jee Sook Hahn, Joon Oh Park, Seok Lee, So Young Chung, Seung Tae Lee, Yoo Hong Min, Yun Woong Ko, Chang Hak Sohn
Department of Internal medicine, Yonsei University, College of Medicine, Seoul, Korea
Department of Internal Medicine, Inje University College of Medicine, Pusan Paik Hospital, Pusan, Korea
Abstract
Pernicious anemia appears to be autoimmune in origin. Autoantibodies such as
anti-parietal cell antibody and anti-intrinsic factor antibody are found in about 90% and
70% of patients, respectively. It is commonly associated with autoimmune disorders of
several organ systems, but rarely with autoimmune hemolytic anemia. When pernicious
anemia and autoimmune hemolytic anemia occurs simultaneously, some diagnostic and
therapeutic difficulties exist.
We experienced a case of pernicious anemia associated with autoimmune hemolytic anemia. The patient was recovered by replacement of vitamin Bl2 and steroid therapy.
Keywords: Pemicious anemia, Autoimmune hemolytic anemia
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