Korean J Hematol 1992; 27(1):
Published online March 31, 1992
© The Korean Society of Hematology
황형기, 이충기, 이관호, 현명수, 심봉섭, 이현우
영남대학교 의과대학 내과학교실
Pleural effusion in patients with multiple myeloma due to plasma cell involvement of the pleura has been reported infrequently and has not yet been reported in Korea.
We report a case of multiple myeloma with pleural involvement presenting dyspnea and pain in the left arm in a 56-year-old women.
On the physical examination, the patient looked chronic ill. There was a palpable mass
on the right skull, firm but not tender and decreased breathing sound in the left lung.
On the neurologic exam, the patient had difficult lateral gaze in the right eyeball movement.
Laboratory findings revealed anemia, elevation of ESR, globulin, RUN and creatinine.
X-ray of the chest showed pleural effusion in the left lung. X-ray of the skull, both humerus and pelvis revealed multiple punched-out osteolytic lesions, pathologic fracture
in the left humerus and compression fracture in the lumbar spine.
The CT examination of chest showed biliateral pleural effusion and rib mass lesions.
Serum and urine electrophoresis revealed a M-spike. Serum and urine immunoelectrophoresis demonstrated an IgG-Kappa monoclonal protein.
Thoracentesis revealed serosanguineous fluid containing atypical plasma cells. Bone marrow examination showed 56% of immature plasma cells.
With first cycle of vincristine, melphalan, prednisonecombination chemotherapy, improvement of pain and eyeball movement, disappearance of pleural effusion was observed. After second cycle of the same chemotherapy, her condition deteriorated and she died due to renal failure.
Keywords Multiple myeloma, Pleural effusion
Korean J Hematol 1992; 27(1): 161-165
Published online March 31, 1992
Copyright © The Korean Society of Hematology.
황형기, 이충기, 이관호, 현명수, 심봉섭, 이현우
영남대학교 의과대학 내과학교실
Hyeong Ki Hwang, Choong Ki Lee, Kwan Ho Lee, Myung Soo Hyun, Bong Sup Shim, Hyun Woo Lee
Department of Internal Medicine, Youngnam University, College of Medicine, Taegu, Korea
Pleural effusion in patients with multiple myeloma due to plasma cell involvement of the pleura has been reported infrequently and has not yet been reported in Korea.
We report a case of multiple myeloma with pleural involvement presenting dyspnea and pain in the left arm in a 56-year-old women.
On the physical examination, the patient looked chronic ill. There was a palpable mass
on the right skull, firm but not tender and decreased breathing sound in the left lung.
On the neurologic exam, the patient had difficult lateral gaze in the right eyeball movement.
Laboratory findings revealed anemia, elevation of ESR, globulin, RUN and creatinine.
X-ray of the chest showed pleural effusion in the left lung. X-ray of the skull, both humerus and pelvis revealed multiple punched-out osteolytic lesions, pathologic fracture
in the left humerus and compression fracture in the lumbar spine.
The CT examination of chest showed biliateral pleural effusion and rib mass lesions.
Serum and urine electrophoresis revealed a M-spike. Serum and urine immunoelectrophoresis demonstrated an IgG-Kappa monoclonal protein.
Thoracentesis revealed serosanguineous fluid containing atypical plasma cells. Bone marrow examination showed 56% of immature plasma cells.
With first cycle of vincristine, melphalan, prednisonecombination chemotherapy, improvement of pain and eyeball movement, disappearance of pleural effusion was observed. After second cycle of the same chemotherapy, her condition deteriorated and she died due to renal failure.
Keywords: Multiple myeloma, Pleural effusion
Seo Jin Park, Hyun Ju Sung, Jeong Ho Kim, Jae Woo Song, Kyung Soon Song
Korean J Hematol 2006; 41(1): 41-45Sung-Hoon Jung, Youngil Koh, Min Kyoung Kim, Jin Seok Kim, Joon Ho Moon, Chang-Ki Min, Dok Hyun Yoon, Sung-Soo Yoon, Je-Jung Lee, Chae Moon Hong, Ka-Won Kang, Jihyun Kwon, Kyoung Ha Kim, Dae Sik Kim, Sung Yong Kim, Sung-Hyun Kim, Yu Ri Kim, Young Rok Do, Yeung-Chul Mun, Sung-Soo Park, Young Hoon Park, Ho Jin Shin, Hyeon-Seok Eom, Sang Eun Yoon, Sang Mee Hwang, Won Sik Lee, Myung-won Lee, Jun Ho Yi, Ji Yun Lee, Ji Hyun Lee, Ho Sup Lee, Sung-Nam Lim, Jihyang Lim, Ho-Young Yhim, Yoon Hwan Chang, Jae-Cheol Jo, Jinhyun Cho, Hyungwoo Cho, Yoon Seok Choi, Hee jeong Cho, Ari Ahn, Jong Han Choi, Hyun Jung Kim and Kihyun Kim
Blood Res 2025; 60():Haerim Chung, Hyunsoo Cho
Blood Res 2023; 58(4): 166-172