Case Report
Korean J Hematol 2005; 40(3):
Published online September 30, 2005
https://doi.org/10.5045/kjh.2005.40.3.197
© The Korean Society of Hematology
공여자백혈구주입술 후 발생한 소아 거대세포바이러스 위장관염 1예
송애경, 김희준, 정현주, 박준은, 정인호, 박준성, 김효철
아주대학교 의과대학 소아과학교실, 외과학교실, 내과학교실
A Pediatric Case with CMV Gastroenteritis after Donor Leukocyte Infusion
There haves been few reports of cytomegalovirus (CMV) gastroenteritis following allogeneic stem cell transplantation, especially in pediatric cases. Herein, we report a case of CMV gastroenteritis in a 10-year-old boy with relapsed juvenile myelomonocytic leukemia who had undergone a donor leukocyte infusion. He presented with a skin rash, diarrhea and abdominal pain following a donor leukocyte infusion. Cramping abdominal pain persisted, even after treatment of the acute graft-versus-host disease. Therefore, gastroduodenoscopy and a gastric mucosal biopsy were performed, after which CMV gastroenteritis was diagnosed. The boy recovered after treatment with ganciclovir and intravenous immunoglobulin.
Keywords CMV gastroenteritis, GVHD, Donor leukocyte infusion
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Case Report
Korean J Hematol 2005; 40(3): 197-200
Published online September 30, 2005 https://doi.org/10.5045/kjh.2005.40.3.197
Copyright © The Korean Society of Hematology.
공여자백혈구주입술 후 발생한 소아 거대세포바이러스 위장관염 1예
송애경, 김희준, 정현주, 박준은, 정인호, 박준성, 김효철
아주대학교 의과대학 소아과학교실, 외과학교실, 내과학교실
A Pediatric Case with CMV Gastroenteritis after Donor Leukocyte Infusion
Ae Kyung Song, Hee Jun Kim, Hyun Joo Jung, Jun Eun Park, In Ho Jeong, Joon Seong Park, Hugh Chul Kim
Departments of, Pediatrics, Surgery, Internal Medicine, Ajou University School of Medicine, Suwon, Korea
Abstract
There haves been few reports of cytomegalovirus (CMV) gastroenteritis following allogeneic stem cell transplantation, especially in pediatric cases. Herein, we report a case of CMV gastroenteritis in a 10-year-old boy with relapsed juvenile myelomonocytic leukemia who had undergone a donor leukocyte infusion. He presented with a skin rash, diarrhea and abdominal pain following a donor leukocyte infusion. Cramping abdominal pain persisted, even after treatment of the acute graft-versus-host disease. Therefore, gastroduodenoscopy and a gastric mucosal biopsy were performed, after which CMV gastroenteritis was diagnosed. The boy recovered after treatment with ganciclovir and intravenous immunoglobulin.
Keywords: CMV gastroenteritis, GVHD, Donor leukocyte infusion
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