Korean J Hematol 2005; 40(2):
Published online June 30, 2005
https://doi.org/10.5045/kjh.2005.40.2.111
© The Korean Society of Hematology
최재명, 이현우, 강석윤, 장준호, 박준성, 최진혁, 임호영, 김효철, 이은소
아주대학교 의과대학 종양혈액내과학교실, 피부과학교실
A twenty-year-old man developed pruritic papules on his right forearm on the 25th day after an allogeneic bone marrow transplantation from an HLA-matched related donor. The skin lesion turned out to be lymphomatoid papulosis, both histologically and immunophenotypically, not a GVHD skin lesion. Lymphomatoid papulosis is a chronic lymphoproliferative disease of the skin, characterized by recurrent crusts of pruritic papules, which initially appearing on the upper trunk and both extremities. The lesions heal spontaneously within 2∼8 weeks, usually leaving slightly depressed oval scars. Histologically, the lesions show wedge-shaped dense dermal infiltrates of lymphoid cells, with numerous eosinophils, neutrophils and atypical lymphocytes. As much as 50% of the infiltrates show atypical lymphocytes, and the dermal vessels may show endothelial swelling, fibrin deposition and red blood cell extravasation. We are reporting a case of spontaneously healing CD56+ lymphomatoid papulosis, in the patient who received bone marrow transplantation, is reported.
Keywords GVHD, Lymphomatoid papulosis, Bone marrow transplantation
Korean J Hematol 2005; 40(2): 111-115
Published online June 30, 2005 https://doi.org/10.5045/kjh.2005.40.2.111
Copyright © The Korean Society of Hematology.
최재명, 이현우, 강석윤, 장준호, 박준성, 최진혁, 임호영, 김효철, 이은소
아주대학교 의과대학 종양혈액내과학교실, 피부과학교실
Jae Myoung Choi, Hyun Woo Lee, Seok Yun Kang, Jun Ho Jang, Joon Seong Park, Jin Hyuk Choi, Ho yeong Lim, Hugh Chul Kim, Eun So Lee
Departments of, Hematology, Oncology and, Dermatology, Ajou University School of Medicine, Suwon, Korea
A twenty-year-old man developed pruritic papules on his right forearm on the 25th day after an allogeneic bone marrow transplantation from an HLA-matched related donor. The skin lesion turned out to be lymphomatoid papulosis, both histologically and immunophenotypically, not a GVHD skin lesion. Lymphomatoid papulosis is a chronic lymphoproliferative disease of the skin, characterized by recurrent crusts of pruritic papules, which initially appearing on the upper trunk and both extremities. The lesions heal spontaneously within 2∼8 weeks, usually leaving slightly depressed oval scars. Histologically, the lesions show wedge-shaped dense dermal infiltrates of lymphoid cells, with numerous eosinophils, neutrophils and atypical lymphocytes. As much as 50% of the infiltrates show atypical lymphocytes, and the dermal vessels may show endothelial swelling, fibrin deposition and red blood cell extravasation. We are reporting a case of spontaneously healing CD56+ lymphomatoid papulosis, in the patient who received bone marrow transplantation, is reported.
Keywords: GVHD, Lymphomatoid papulosis, Bone marrow transplantation
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