Korean J Hematol 2009; 44(4):
Published online December 30, 2009
https://doi.org/10.5045/kjh.2009.44.4.294
© The Korean Society of Hematology
이재현, 김달식, 이혜수, 최삼임, 조용곤
전북대학 의과대학 임상연구소 진단감사의학과
Immune thrombocytopenia is a rare complication associated with vancomycin. A 76-year-old male patient who was treated with vancomycin experienced severe thrombocytopenia and refractoriness as a result of platelet transfusion. Vancomycin-dependent antibodies in his thrombocytopenic serum were detected by flow cytometric analysis. The mechanism of thrombocytopenia is probably related to immunological destruction, as strongly suggested by its association with a specific drug-dependent anti-platelet antibody. (Korean J Hematol 2009;44:294-297.)
Keywords Thrombocytopenia, Vancomycin, Drug-induced
Korean J Hematol 2009; 44(4): 294-297
Published online December 30, 2009 https://doi.org/10.5045/kjh.2009.44.4.294
Copyright © The Korean Society of Hematology.
이재현, 김달식, 이혜수, 최삼임, 조용곤
전북대학 의과대학 임상연구소 진단감사의학과
Jae Hyeon Lee, Dal Sik Kim, Hye Soo Lee, Sam Im Choi, Yong Gon Cho
Department of Laboratory Medicine, Chonbuk National University Medical School,Research Institute of Clinical Medicine, Chonbuk National University, Jeonju, Korea
Immune thrombocytopenia is a rare complication associated with vancomycin. A 76-year-old male patient who was treated with vancomycin experienced severe thrombocytopenia and refractoriness as a result of platelet transfusion. Vancomycin-dependent antibodies in his thrombocytopenic serum were detected by flow cytometric analysis. The mechanism of thrombocytopenia is probably related to immunological destruction, as strongly suggested by its association with a specific drug-dependent anti-platelet antibody. (Korean J Hematol 2009;44:294-297.)
Keywords: Thrombocytopenia, Vancomycin, Drug-induced
Ka‑Won Kang
Blood Res 2024; 59():Young Rok Do, Yunsuk Choi, Mi Hwa Heo, Jin Seok Kim, Jae-ho Yoon, Je-Hwan Lee, Joon Seong Park, Sang Kyun Sohn, Sung Hyun Kim, Sungnam Lim, Joo Seop Chung, Deog-Yeon Jo, Hyeon Seok Eom, Hawk Kim, So Yeon Jeon, Jong-Ho Won, Hee Jeong Lee, Jung Won Shin, Jun-Ho Jang, Sung-Soo Yoon
Blood Res 2022; 57(3): 207-215Young Hoon Park
Blood Res 2022; 57(S1): S79-S85