Case Report

Korean J Hematol 2008; 43(1):

Published online March 30, 2008

https://doi.org/10.5045/kjh.2008.43.1.53

© The Korean Society of Hematology

소아 급성림프모구백혈병 환자에서 6-mercaptopurine과 6-thioguanine 사용 후 발생한 급성 췌장염 1예

윤종형, 백재숙, 김은경, 강형진, 신희영, 안효섭

서울대학교 의과대학 소아과학교실암연구소

Pancreatitis Induced by 6-mercaptopurine and 6-thioguanine in Childhood Acute Lymphoblastic Leukemia

Jong Hyung Yoon, Jae Suk Baek, Eun Kyung Kim, Hyoung Jin Kang, Hee Young Shin, Hyo Seop Ahn,

Department of Pediatrics, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Abstract

Although pancreatitis is known as a common complication during the treatment of acute lymphoblastic leukemia, acute pancreatitis that's induced by 6-mercaptopurine or 6-thioguanine is very uncommon. We experienced the case of an 11-year-old boy with consecutive acute pancreatitis, and this was induced by 6-mercaptopurine and 6-thioguanine during maintenance chemotherapy of childhood acute lymphoblastic leukemia. We report here on this along with a review of the pertinent literature.

Keywords Pancreatitis, 6-mercaptopurine, 6-thioguanine, Acute lymphoblastic leukemia

Article

Case Report

Korean J Hematol 2008; 43(1): 53-57

Published online March 30, 2008 https://doi.org/10.5045/kjh.2008.43.1.53

Copyright © The Korean Society of Hematology.

소아 급성림프모구백혈병 환자에서 6-mercaptopurine과 6-thioguanine 사용 후 발생한 급성 췌장염 1예

윤종형, 백재숙, 김은경, 강형진, 신희영, 안효섭

서울대학교 의과대학 소아과학교실암연구소

Pancreatitis Induced by 6-mercaptopurine and 6-thioguanine in Childhood Acute Lymphoblastic Leukemia

Jong Hyung Yoon, Jae Suk Baek, Eun Kyung Kim, Hyoung Jin Kang, Hee Young Shin, Hyo Seop Ahn,

Department of Pediatrics, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

Abstract

Although pancreatitis is known as a common complication during the treatment of acute lymphoblastic leukemia, acute pancreatitis that's induced by 6-mercaptopurine or 6-thioguanine is very uncommon. We experienced the case of an 11-year-old boy with consecutive acute pancreatitis, and this was induced by 6-mercaptopurine and 6-thioguanine during maintenance chemotherapy of childhood acute lymphoblastic leukemia. We report here on this along with a review of the pertinent literature.

Keywords: Pancreatitis, 6-mercaptopurine, 6-thioguanine, Acute lymphoblastic leukemia

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