Korean J Hematol 2007; 42(3):
Published online September 30, 2007
https://doi.org/10.5045/kjh.2007.42.3.288
© The Korean Society of Hematology
우찬욱, 재서진, 김수영, 최병민, 이정화, 이광철
고려대 안산병원 소아과,
고려대 안암병원 소아과
Autoimmune hemolytic anemia (AIHA) is characterized by the production of antibodies directed against red blood cells (RBCs). It is usually accompanied by normal white blood cell (WBC) and platelet counts. Severe leukocytosis and thrombocytosis in AIHA are rare. Here, we report a 3-year-old female child who showed AIHA by warm antibody testing with both leukocytosis and thrombocytosis. The patient was treated with oral steroids for 5 days. During treatment, the leukocytosis was noted on hospital day 3 and was up to 60.87×109/L. In addition, the thrombocytosis persisted at up to 725×109/L. After day 7, the WBC and platelet counts returned to the normal range. The clinical condition and vital signs improved. The patient was discharged on day 12. This case demonstrated that patients with primary AIHA, may also have leukocytosis and thrombocytosis.
Keywords Autoimmune hemolytic anemia, Leukocytosis, Thrombocytosis
Korean J Hematol 2007; 42(3): 288-291
Published online September 30, 2007 https://doi.org/10.5045/kjh.2007.42.3.288
Copyright © The Korean Society of Hematology.
우찬욱, 재서진, 김수영, 최병민, 이정화, 이광철
고려대 안산병원 소아과,
고려대 안암병원 소아과
Seo Jin Jea, Soo Young Kim, Byung Min Choi, Jung Hwa Lee, Kwang Chul Lee, Chan Wook Woo
Department of Pediatrics, College of Medicine, Korea University Ansan Hospital, Ansan, Korea
University Anam Hospital, Seoul, Korea
Autoimmune hemolytic anemia (AIHA) is characterized by the production of antibodies directed against red blood cells (RBCs). It is usually accompanied by normal white blood cell (WBC) and platelet counts. Severe leukocytosis and thrombocytosis in AIHA are rare. Here, we report a 3-year-old female child who showed AIHA by warm antibody testing with both leukocytosis and thrombocytosis. The patient was treated with oral steroids for 5 days. During treatment, the leukocytosis was noted on hospital day 3 and was up to 60.87×109/L. In addition, the thrombocytosis persisted at up to 725×109/L. After day 7, the WBC and platelet counts returned to the normal range. The clinical condition and vital signs improved. The patient was discharged on day 12. This case demonstrated that patients with primary AIHA, may also have leukocytosis and thrombocytosis.
Keywords: Autoimmune hemolytic anemia, Leukocytosis, Thrombocytosis
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