Case Report
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Korean J Hematol 2012; 47(4):
Published online December 31, 2012
https://doi.org/10.5045/kjh.2012.47.4.298
© The Korean Society of Hematology
Complications following an unnecessary peri-operative plasma transfusion and literature review
1Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
2The Institute for Transfusion Medicine, Pittsburgh, PA, USA.
3Department of Anesthesiology, Magee Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Correspondence to : Correspondence to Mark H. Yazer, M.D. The Institute for Transfusion Medicine, University of Pittsburgh Medical Center, 3636 Blvd of the Allies, Pittsburgh, PA, 15213, USA. Tel: +1-412-209-7522, Fax: +1-412-209-7325, myazer@itxm.org
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Plasma is used to correct coagulopathies, but not all coagulation abnormalities are clinically significant enough to require correction before an invasive procedure. We report an 82 year old female who, in response to a mildly prolonged INR of unknown etiology, was unnecessarily transfused with plasma in advance of elective surgery. The patient suffered a moderately severe transfusion reaction, including hives and voice hoarseness, which caused a 4-week delay in her surgery. This delay and adverse reaction could have been avoided had the principles of evidence based plasma therapy, which we herein review, been followed and if the etiology of the mildly elevated INR been investigated before the day of her surgery.
Keywords Plasma, FFP, Transfusion, Allergic, Reaction, Complication
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Case Report
Korean J Hematol 2012; 47(4): 298-301
Published online December 31, 2012 https://doi.org/10.5045/kjh.2012.47.4.298
Copyright © The Korean Society of Hematology.
Complications following an unnecessary peri-operative plasma transfusion and literature review
Jay S. Raval1,2, Jonathan H. Waters3, Darrell J. Triulzi1,2, and Mark H. Yazer1,2*
1Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
2The Institute for Transfusion Medicine, Pittsburgh, PA, USA.
3Department of Anesthesiology, Magee Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Correspondence to: Correspondence to Mark H. Yazer, M.D. The Institute for Transfusion Medicine, University of Pittsburgh Medical Center, 3636 Blvd of the Allies, Pittsburgh, PA, 15213, USA. Tel: +1-412-209-7522, Fax: +1-412-209-7325, myazer@itxm.org
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Plasma is used to correct coagulopathies, but not all coagulation abnormalities are clinically significant enough to require correction before an invasive procedure. We report an 82 year old female who, in response to a mildly prolonged INR of unknown etiology, was unnecessarily transfused with plasma in advance of elective surgery. The patient suffered a moderately severe transfusion reaction, including hives and voice hoarseness, which caused a 4-week delay in her surgery. This delay and adverse reaction could have been avoided had the principles of evidence based plasma therapy, which we herein review, been followed and if the etiology of the mildly elevated INR been investigated before the day of her surgery.
Keywords: Plasma, FFP, Transfusion, Allergic, Reaction, Complication
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