Case Report
Korean J Hematol 2007; 42(2):
Published online June 30, 2007
https://doi.org/10.5045/kjh.2007.42.2.157
© The Korean Society of Hematology
Littoral Cell Angioma에 동반된 Bicytopenia 1예
송무곤, 설영미, 박영은, 안성규, 최영진, 신호진, 정주섭, 조군제
부산대학교 의과대학 내과학교실
A Case of Bicytopenia Combined with Littoral Cell Angioma
Littoral cell angioma is a recently described vascular tumor of spleen with an unknown etiology. We present a case in a 74-year-old woman with severe anemia, thrombocytopenia and palpable splenomegaly. The computed tomography of abdomen showed well-defined multiple nodules in spleen. Splenectomy was performed and the histological and immunohistochemical features of splenic tumor were consistent with a littoral cell angioma. The patients had persistent anemia and thrombocytopenia after splenectomy. We suggest hepatic destruction or other autoimmune mechanism contributes persistent bicytopenia. This case illustrated the refractory bicytopenia combined with littoral cell angioma.
Keywords Littoral cell angioma, Anemia, Thrombocytopenia, Splenomegaly
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Case Report
Korean J Hematol 2007; 42(2): 157-161
Published online June 30, 2007 https://doi.org/10.5045/kjh.2007.42.2.157
Copyright © The Korean Society of Hematology.
Littoral Cell Angioma에 동반된 Bicytopenia 1예
송무곤, 설영미, 박영은, 안성규, 최영진, 신호진, 정주섭, 조군제
부산대학교 의과대학 내과학교실
A Case of Bicytopenia Combined with Littoral Cell Angioma
Moo Kon Song, Young Mi Seol, Young Eun Park, Sung Kyu An, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Goon Jae Cho
Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea
Abstract
Littoral cell angioma is a recently described vascular tumor of spleen with an unknown etiology. We present a case in a 74-year-old woman with severe anemia, thrombocytopenia and palpable splenomegaly. The computed tomography of abdomen showed well-defined multiple nodules in spleen. Splenectomy was performed and the histological and immunohistochemical features of splenic tumor were consistent with a littoral cell angioma. The patients had persistent anemia and thrombocytopenia after splenectomy. We suggest hepatic destruction or other autoimmune mechanism contributes persistent bicytopenia. This case illustrated the refractory bicytopenia combined with littoral cell angioma.
Keywords: Littoral cell angioma, Anemia, Thrombocytopenia, Splenomegaly
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