Case Report

Korean J Hematol 2009; 44(4):

Published online December 30, 2009

https://doi.org/10.5045/kjh.2009.44.4.268

© The Korean Society of Hematology

담낭에 단독으로 재발한 림프절외(Extranodal) NK/T세포 림프종 1예

고희자 양미연 김한조 윤진아 김현정 이상철 배상병 김찬규 이남수 박성규 이규택 원종호 홍대식 박희숙 김희경

순천향대학교 의과대학 내과학교실 혈액종양내과, 병리학교실

A Case of Solitary Involved NK-T Cell Lymphoma on the Gallbladder

Hee Ja Ko, Mi Yean Yang, Han Jo Kim, Jin A Yun, Hyun Jung Kim, Sang Cheol Lee, Sang Byung Bae, Chan Kyu Kim, Nam Su Lee, Seong Kyu Park, Kyu Teak Lee, Jong Ho Won, Dae Sik Hong, Hee Sook Park, Hee Kyung Kim

Departments of Internal Medicine and Pathology, University of Soonchunhyang Collage of Medicine, Bucheon, Korea

Abstract

Extranodal NK-T cell lymphoma is a subtype of non-Hodgkin's lymphoma (NHL) and this most commonly affects the nasal and paranasal cavities. Primary lymphoma of the gallbladder is extremely rare and solitary relapsed extranodal NK-T cell lymphoma of the gallbladder has not yet been reported in Korea. We experienced a case of a solitary relapsed extranodal NK-T cell lymphoma of the gallbladder. One year earlier, a 55-year-old man was diagnosed with extranodal NK-T cell lymphoma of the anus, and he underwent six cycles of chemotherapy with CHOP (cyclophosphamide, adriamycin, vincristine and prednisone), and he achieved complete remission. The patient was admitted for right upper quadrant pain. Computed tomography (CT) performed on readmission revealed gallbladder wall thickening. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed hypermetabolic lesions along the gallbladder wall. The specimen obtained at cholecystectomy revealed CD3(+) and CD56(+) lymphoma, which is characteristic of NK-T cell lymphoma. (Korean J Hematol 2009;44:268-272.)

Keywords Extranodal NK-T cell lymphoma, Gallbladder cancer, Non-Hodgkin's lymphoma

Article

Case Report

Korean J Hematol 2009; 44(4): 268-272

Published online December 30, 2009 https://doi.org/10.5045/kjh.2009.44.4.268

Copyright © The Korean Society of Hematology.

담낭에 단독으로 재발한 림프절외(Extranodal) NK/T세포 림프종 1예

고희자 양미연 김한조 윤진아 김현정 이상철 배상병 김찬규 이남수 박성규 이규택 원종호 홍대식 박희숙 김희경

순천향대학교 의과대학 내과학교실 혈액종양내과, 병리학교실

A Case of Solitary Involved NK-T Cell Lymphoma on the Gallbladder

Hee Ja Ko, Mi Yean Yang, Han Jo Kim, Jin A Yun, Hyun Jung Kim, Sang Cheol Lee, Sang Byung Bae, Chan Kyu Kim, Nam Su Lee, Seong Kyu Park, Kyu Teak Lee, Jong Ho Won, Dae Sik Hong, Hee Sook Park, Hee Kyung Kim

Departments of Internal Medicine and Pathology, University of Soonchunhyang Collage of Medicine, Bucheon, Korea

Abstract

Extranodal NK-T cell lymphoma is a subtype of non-Hodgkin's lymphoma (NHL) and this most commonly affects the nasal and paranasal cavities. Primary lymphoma of the gallbladder is extremely rare and solitary relapsed extranodal NK-T cell lymphoma of the gallbladder has not yet been reported in Korea. We experienced a case of a solitary relapsed extranodal NK-T cell lymphoma of the gallbladder. One year earlier, a 55-year-old man was diagnosed with extranodal NK-T cell lymphoma of the anus, and he underwent six cycles of chemotherapy with CHOP (cyclophosphamide, adriamycin, vincristine and prednisone), and he achieved complete remission. The patient was admitted for right upper quadrant pain. Computed tomography (CT) performed on readmission revealed gallbladder wall thickening. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed hypermetabolic lesions along the gallbladder wall. The specimen obtained at cholecystectomy revealed CD3(+) and CD56(+) lymphoma, which is characteristic of NK-T cell lymphoma. (Korean J Hematol 2009;44:268-272.)

Keywords: Extranodal NK-T cell lymphoma, Gallbladder cancer, Non-Hodgkin's lymphoma

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