Korean J Hematol 2007; 42(4):
Published online December 30, 2007
https://doi.org/10.5045/kjh.2007.42.4.414
© The Korean Society of Hematology
윤동환, 박경태, 박병규, 임연정, 홍은경, 이강식, 김현정, 김홍준
경희대학교 의과대학 재활의학교실,
을지대학교 의과대학 재활의학교실,
국립암센터 소아종양클리닉,
한양대학교 의과대학 소아청소년학교실,
국립암센터 병리과
Ganglioneuroblastoma is a rare tumor originating from the sympathetic chain. It is intermediate between the highly malignant neuroblastoma and the benign ganglioneuroma. The predilection sites of ganglioneuroblastoma are the retroperitoneum and mediastinum but involvement of the structures around the spinal cord is infrequent. A 4 year-old girl who had progressive weakness in both lower extremities had a tiptoe gait for 2 months. A magnetic resonance imaging (MRI) study revealed a heterogeneous enhancing mass in the right mediastinum and paraspinal areas. A biopsy of the mass confirmed a ganglioneuroblastoma with many neuroblasts and nodules of ganglion cells. This is an unusual case of a child with spastic paraplegia caused by ganglioneuroblastoma of the thoracic cavity.
Keywords Ganglioneuroblastoma, Mediastinum, Spinal cord, Paraplegia
Korean J Hematol 2007; 42(4): 414-418
Published online December 30, 2007 https://doi.org/10.5045/kjh.2007.42.4.414
Copyright © The Korean Society of Hematology.
윤동환, 박경태, 박병규, 임연정, 홍은경, 이강식, 김현정, 김홍준
경희대학교 의과대학 재활의학교실,
을지대학교 의과대학 재활의학교실,
국립암센터 소아종양클리닉,
한양대학교 의과대학 소아청소년학교실,
국립암센터 병리과
Dong Hwan Yun, Kyung Tae Park, Byung Kiu Park, Yun Jung Im, Eun Kyung Hong, Kang Sik Lee, Hyun Jung Kim, Hong Joon Kim,
Department of Physical Medicine Rehabilitation, Kyung Hee University College of Medicine
Department of Rehabilitation Medicine,Eulji University School of Medicine
Pediatric Oncology Clinic, National Cancer Center
Department of Pediatrics,College of Medicine, Hanyang University
Department of Pathology, National Cancer Center, Seoul, Korea
Ganglioneuroblastoma is a rare tumor originating from the sympathetic chain. It is intermediate between the highly malignant neuroblastoma and the benign ganglioneuroma. The predilection sites of ganglioneuroblastoma are the retroperitoneum and mediastinum but involvement of the structures around the spinal cord is infrequent. A 4 year-old girl who had progressive weakness in both lower extremities had a tiptoe gait for 2 months. A magnetic resonance imaging (MRI) study revealed a heterogeneous enhancing mass in the right mediastinum and paraspinal areas. A biopsy of the mass confirmed a ganglioneuroblastoma with many neuroblasts and nodules of ganglion cells. This is an unusual case of a child with spastic paraplegia caused by ganglioneuroblastoma of the thoracic cavity.
Keywords: Ganglioneuroblastoma, Mediastinum, Spinal cord, Paraplegia
Young Hee Nam, Ji Hyun Lee, Kyung A Kwon, Suee Lee, Sung Yong Oh, Sung Hyun Kim, Hyuk Chan Kwon, Jin Yeong Han, Sook Hee Hong, Hyo Jin Kim
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