Korean J Hematol 2003; 38(4):
Published online December 31, 2003
© The Korean Society of Hematology
최동석, 서영태, 최성호, 김혜진, 김봉석
서울보훈병원 내과
Helicobacter pylori (H. pylori) has been recognized as a main cause of gastritis and most cases of peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. An immunological response to H. pylori infection has been suggested to play a major role in determining gastroduodenal damage through the production of cytokines and the autoantibody against gastric epithelial cell. H. pylori has been implicated in the pathogenesis of some autoimmune disease, such as Sjogren disease, Henoch-Schnlein purpura, rheumatoid arthritis, autoimmune thyroid disease, and idiopathic thrombocytopenic purpura (ITP). Serveral studies recently showed a high prevalence of H. pylori infection in patients with ITP and reported a platelet recovery after bacterial eradication therapy. We report a case of a 54-year- old man with chronic ITP who was resolved after eradication of H. pylori.
Keywords Idiopathoic thrombocytopenic purpura(ITP), Helicobacter pylori
Korean J Hematol 2003; 38(4): 270-273
Published online December 31, 2003
Copyright © The Korean Society of Hematology.
최동석, 서영태, 최성호, 김혜진, 김봉석
서울보훈병원 내과
Dong Seog Choi, Yeong Tae Seo, Seong Ho Choi, Hye Jin Kim, Bong Seog Kim
Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea.
Helicobacter pylori (H. pylori) has been recognized as a main cause of gastritis and most cases of peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. An immunological response to H. pylori infection has been suggested to play a major role in determining gastroduodenal damage through the production of cytokines and the autoantibody against gastric epithelial cell. H. pylori has been implicated in the pathogenesis of some autoimmune disease, such as Sjogren disease, Henoch-Schnlein purpura, rheumatoid arthritis, autoimmune thyroid disease, and idiopathic thrombocytopenic purpura (ITP). Serveral studies recently showed a high prevalence of H. pylori infection in patients with ITP and reported a platelet recovery after bacterial eradication therapy. We report a case of a 54-year- old man with chronic ITP who was resolved after eradication of H. pylori.
Keywords: Idiopathoic thrombocytopenic purpura(ITP), Helicobacter pylori