Korean J Hematol 2003; 38(2):
Published online June 30, 2003
© The Korean Society of Hematology
원발성삼출액림프종 3례
강소영, 박찬정, 허주령, 강윤구, 이영상, 지현숙
울산대학교 의과대학 서울아산병원 진담검사의학과,
울산대학교 의과대학 서울아산병원 진단병리과,
울산대학교 의과대학 서울아산병원 내과
Three Cases of Primary Effusion Lymphoma
Primary effusion lymphoma (PEL) is a recently described rare type of non-Hodgkin's lymphoma which develops in serous body cavity without clinically identifiable tumor masses. Human herpesvirus (HHV)-8 was recognized to play a pathogenic role in the development of PEL in immunocompromised patients such as human immunodeficiency virus (HIV) positive patients or elderly. However, several cases of HHV-8 negative PEL have been reported. Here we describe a case of HHV-8 positive PEL with both of
hepatocellular carcinoma and liver cirrhosis and two cases of HHV-8 negative PEL with liver cirrhosis and fatty liver each. Considering the reported and current HHV-8 negative PEL cases, we need to expand the concept of PEL.
Keywords Primary effusion lymphoma; Human herpesvirus-8; Translocation(8;14);
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Korean J Hematol 2003; 38(2): 136-141
Published online June 30, 2003
Copyright © The Korean Society of Hematology.
원발성삼출액림프종 3례
강소영, 박찬정, 허주령, 강윤구, 이영상, 지현숙
울산대학교 의과대학 서울아산병원 진담검사의학과,
울산대학교 의과대학 서울아산병원 진단병리과,
울산대학교 의과대학 서울아산병원 내과
Three Cases of Primary Effusion Lymphoma
So Young Kang, Chan Jeoung Park, Joo Ryung Huh, Yun Goo Kang, Young Sang Lee, Hyun Sook Chi
Department of Laboratory Medicine, Pathology, Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Abstract
Primary effusion lymphoma (PEL) is a recently described rare type of non-Hodgkin's lymphoma which develops in serous body cavity without clinically identifiable tumor masses. Human herpesvirus (HHV)-8 was recognized to play a pathogenic role in the development of PEL in immunocompromised patients such as human immunodeficiency virus (HIV) positive patients or elderly. However, several cases of HHV-8 negative PEL have been reported. Here we describe a case of HHV-8 positive PEL with both of
hepatocellular carcinoma and liver cirrhosis and two cases of HHV-8 negative PEL with liver cirrhosis and fatty liver each. Considering the reported and current HHV-8 negative PEL cases, we need to expand the concept of PEL.
Keywords: Primary effusion lymphoma, Human herpesvirus-8, Translocation(8,14),
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