Case Report

Korean J Hematol 2006; 41(2):

Published online June 30, 2006

https://doi.org/10.5045/kjh.2006.41.2.115

© The Korean Society of Hematology

치료받지 않은 급성골수성백혈병 환자의 대장에서 발생한 침습성 Aspergillosis 1예

문지윤, 최영진, 신호진, 정주섭, 송무곤, 한동철, 박지영, 김경엽, 김활웅, 조군제

부산대학교 의과대학, 내과학교실 혈액종양내과, 병리학교실

A Case of an Untreated Acute Myeloid Leukemia Patient with Invasive Aspergillosis that Developed at the Colon

Ji Yoon Moon, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Moo Kon Song, Dong Cheul Han, Ji Young Park, Kyung Yup Kim, Hwal Woong Kim, Goon Jae Cho

Departments of, Internal Medicine and, Pathology, Pusan National University College of Medicine, Busan, Korea

Abstract

Invasive aspergillosis needs to be paid extra attention to these day since chemotherapy and stem cell transplantation bring about immune suppression. The lung is the main portal of entry and once involved, invasive aspergillosis may be delivered by hematogenous spread into the central nervous system, liver, spleen, gut and adrenal gland. However infections through the gastrointestinal track are not common. In these cases, abdominal pain and diarrhea can be the major symptoms and amphotericin B is the treatment of choice. We report here on a patient with untreated acute myeloid leukemia who suffered from bloody diarrhea without any lung lesion; this patient had ulcer close to cecum on colonoscopy, and then he was diagnosed as suffering with aspergillosis with H&E staining and PAS staining on the biopsy specimen.

Keywords Aspergillosis, Leukemia, Gastrointestinal tract

Article

Case Report

Korean J Hematol 2006; 41(2): 115-118

Published online June 30, 2006 https://doi.org/10.5045/kjh.2006.41.2.115

Copyright © The Korean Society of Hematology.

치료받지 않은 급성골수성백혈병 환자의 대장에서 발생한 침습성 Aspergillosis 1예

문지윤, 최영진, 신호진, 정주섭, 송무곤, 한동철, 박지영, 김경엽, 김활웅, 조군제

부산대학교 의과대학, 내과학교실 혈액종양내과, 병리학교실

A Case of an Untreated Acute Myeloid Leukemia Patient with Invasive Aspergillosis that Developed at the Colon

Ji Yoon Moon, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Moo Kon Song, Dong Cheul Han, Ji Young Park, Kyung Yup Kim, Hwal Woong Kim, Goon Jae Cho

Departments of, Internal Medicine and, Pathology, Pusan National University College of Medicine, Busan, Korea

Abstract

Invasive aspergillosis needs to be paid extra attention to these day since chemotherapy and stem cell transplantation bring about immune suppression. The lung is the main portal of entry and once involved, invasive aspergillosis may be delivered by hematogenous spread into the central nervous system, liver, spleen, gut and adrenal gland. However infections through the gastrointestinal track are not common. In these cases, abdominal pain and diarrhea can be the major symptoms and amphotericin B is the treatment of choice. We report here on a patient with untreated acute myeloid leukemia who suffered from bloody diarrhea without any lung lesion; this patient had ulcer close to cecum on colonoscopy, and then he was diagnosed as suffering with aspergillosis with H&E staining and PAS staining on the biopsy specimen.

Keywords: Aspergillosis, Leukemia, Gastrointestinal tract

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