Korean J Hematol 2002; 37(4):
Published online December 31, 2002
© The Korean Society of Hematology
임신 중 발견된 비호지킨림프종의 성공적 치료와 장기 경과관찰
황인규, 심기식, 김석현, 이경원, 이원섭, 윤희상, 고경혁, 이종석
경상대학교 의과대학 내과학교실,
경상대학교 의과대학 소아과학교실,
경상대학교 의과대학 병리학교실
Successful Treatment of Non-Hodgkin's Lymphoma during Pregnancy and Long-term Follow-up of a Child born to the Mother
The occurrence of Non-Hodgkin's lymphoma (NHL) during pregnancy is rare. The optimal management of NHL during pregnancy requires special considerations. Because of their rapid progression, women with aggressive NHL should receive standard chemotherapy despite the potential risk to the developing fetus. We experienced a case of 30-year-old pregnant woman diagnosed as a diffuse large B cell NHL at 28 weeks of gestation, who was taken 4 cycles of CHOP combination chemotherapy and delivered a male baby
weighing 2660g at 39 weeks of gestation. Following delivery, she received additional 3 cycles of chemotherapy with 4500c㏉ of radiotherapy on the neck. While she has been in complete remission of NHL over 6 years, her baby have developed mild developmental retardation.
Keywords Non-Hodgkin's lymphoma; Pregnancy; Chemotherapy;
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Korean J Hematol 2002; 37(4): 302-306
Published online December 31, 2002
Copyright © The Korean Society of Hematology.
임신 중 발견된 비호지킨림프종의 성공적 치료와 장기 경과관찰
황인규, 심기식, 김석현, 이경원, 이원섭, 윤희상, 고경혁, 이종석
경상대학교 의과대학 내과학교실,
경상대학교 의과대학 소아과학교실,
경상대학교 의과대학 병리학교실
Successful Treatment of Non-Hodgkin's Lymphoma during Pregnancy and Long-term Follow-up of a Child born to the Mother
In Gyu Hwang, Ki Shik Shim, Seok Hyun Kim, Gyeong Won Lee, Won Sup Lee, Hee Shang Youn, Gyung Hyuck Ko, Jong Seok Lee
Department of Internal Medicine, Pediatrics, Pathology, Gueong, Sang National University College of Medicine, Jinju, Korea
Abstract
The occurrence of Non-Hodgkin's lymphoma (NHL) during pregnancy is rare. The optimal management of NHL during pregnancy requires special considerations. Because of their rapid progression, women with aggressive NHL should receive standard chemotherapy despite the potential risk to the developing fetus. We experienced a case of 30-year-old pregnant woman diagnosed as a diffuse large B cell NHL at 28 weeks of gestation, who was taken 4 cycles of CHOP combination chemotherapy and delivered a male baby
weighing 2660g at 39 weeks of gestation. Following delivery, she received additional 3 cycles of chemotherapy with 4500c㏉ of radiotherapy on the neck. While she has been in complete remission of NHL over 6 years, her baby have developed mild developmental retardation.
Keywords: Non-Hodgkin's lymphoma, Pregnancy, Chemotherapy,
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