Korean J Hematol 2002; 37(1):
Published online March 31, 2002
© The Korean Society of Hematology
크론씨병에 동반된 골수이형성증후군 2례
김현진, 김진석, 김동기, 이승태, 정준원, 장준호, 서형찬, 민유홍, 한지숙, 고윤웅, 김원호
연세대학교 의과대학 내과학교실
Two Cases of Crohn's Disease with Myelodysplastic Syndrome
Myelodysplastic syndromes (MDS) are bone marrow stem cell disorders characterized by dysplastic hematopoiesis leading to peripheral pancytopenias, and by a high risk of progression to acute myeloid leukemia. Several immunological disorders, particularly relapsing polychondritis, seronegative arthritis and cutaneous vasculitis have been described in association with MDS. Crohn's disease is an inflammatory bowel disease characterized by inflammatory, ulcerative bowel lesions and frequent association with systemic manifestations. Recently, some researchers have suggested that an association may exist between MDS and inflammatory bowel diseases, especially Cronh's disease, based on concomittant findigns of both disorders in some reported patients.
We report here two cases who developed MDS and Crohn's disease concurrently, and review previously reported literatures.
Keywords Myelodysplastic syndrome; Crohn's disease;
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Korean J Hematol 2002; 37(1): 70-75
Published online March 31, 2002
Copyright © The Korean Society of Hematology.
크론씨병에 동반된 골수이형성증후군 2례
김현진, 김진석, 김동기, 이승태, 정준원, 장준호, 서형찬, 민유홍, 한지숙, 고윤웅, 김원호
연세대학교 의과대학 내과학교실
Two Cases of Crohn's Disease with Myelodysplastic Syndrome
Hyun Jin Kim, Jin Seok Kim, Dong Ki Kim, Seung Tae Lee, June Won Cheong, Joon Ho Jang, Hyung Chan Suh, Yoo Hong Min, Jee Sook Hahn, Yun Woong Ko, Won Ho Kim
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
Abstract
Myelodysplastic syndromes (MDS) are bone marrow stem cell disorders characterized by dysplastic hematopoiesis leading to peripheral pancytopenias, and by a high risk of progression to acute myeloid leukemia. Several immunological disorders, particularly relapsing polychondritis, seronegative arthritis and cutaneous vasculitis have been described in association with MDS. Crohn's disease is an inflammatory bowel disease characterized by inflammatory, ulcerative bowel lesions and frequent association with systemic manifestations. Recently, some researchers have suggested that an association may exist between MDS and inflammatory bowel diseases, especially Cronh's disease, based on concomittant findigns of both disorders in some reported patients.
We report here two cases who developed MDS and Crohn's disease concurrently, and review previously reported literatures.
Keywords: Myelodysplastic syndrome, Crohn's disease,
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