Korean J Hematol 2001; 36(4):
Published online December 31, 2001
© The Korean Society of Hematology
박진아, 김기원, 박석영, 박희철, 윤종현, 김희정, 이은희, 이혜경, 계철승
가톨릭대학교 의과대학 내과학교실,
가톨릭대학교 의과대학 임상병리학교실,
가톨릭대학교 의과대학 치료방사선과학교실
Epstein-Barr virus (EBV), a human lymphotropic herpesvirus, is presently the best known viral contributor to the development of human lymphomas and transforms normal resting B cells into immunoblasts. Especially a positive correlation has been found between the EBV-associated lymphadenopathy and the later develpoment of EBV-carrying lymphoma in patients with acquired immune deficiency syndorme. Anaplastic large cell lymphoma(ALCL) is a clinicopathologically distinct category of non-Hodgkin's
lymphoma (NHL) and classified as T-/null-cell type lymphomas in the revised European-American Classification of lymphoid neoplasms. We report a patient with EBV-associated B-cell ALCL and HIV positive patient usually has B-cell phenotype, so this lymphoma should be distinguished from the classical ALCL as were defined by the revised European-American Classification of lymphoid neoplasms.
Keywords HIV, EBV, Anaplastic large cell lymphoma
Korean J Hematol 2001; 36(4): 355-358
Published online December 31, 2001
Copyright © The Korean Society of Hematology.
박진아, 김기원, 박석영, 박희철, 윤종현, 김희정, 이은희, 이혜경, 계철승
가톨릭대학교 의과대학 내과학교실,
가톨릭대학교 의과대학 임상병리학교실,
가톨릭대학교 의과대학 치료방사선과학교실
Jin Ah Park, Kee Won Kim, Suk Young Park, Hee Chul Park, Chong Hyeon Yoon, Hee Jung Kim, Eun Hee Lee, Hye Kyung Lee, Chul Seung Kay
Department of Internal Meidicine, Clinical Pathology, Therapeutic Radiology, College of Medicine, The Catholic University fo Korea, Seoul, Korea
Epstein-Barr virus (EBV), a human lymphotropic herpesvirus, is presently the best known viral contributor to the development of human lymphomas and transforms normal resting B cells into immunoblasts. Especially a positive correlation has been found between the EBV-associated lymphadenopathy and the later develpoment of EBV-carrying lymphoma in patients with acquired immune deficiency syndorme. Anaplastic large cell lymphoma(ALCL) is a clinicopathologically distinct category of non-Hodgkin's
lymphoma (NHL) and classified as T-/null-cell type lymphomas in the revised European-American Classification of lymphoid neoplasms. We report a patient with EBV-associated B-cell ALCL and HIV positive patient usually has B-cell phenotype, so this lymphoma should be distinguished from the classical ALCL as were defined by the revised European-American Classification of lymphoid neoplasms.
Keywords: HIV, EBV, Anaplastic large cell lymphoma
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