Korean J Hematol 1998; 33(2):

Published online June 30, 1998

© The Korean Society of Hematology

만성 B형 간염환자에서 발생한 자가면역성 용혈성 빈혈 1례

강효승, 이희영, 김우석, 이기섭, 김병일, 여운철, 이정호, 이명래, 변동일, 윤미애, 이수남

인천기독병원 내과,
인천기독병원 임상병리과,
인천기독병원 해부병리과

A Case of Autoimmune Hemolytic Anemia Developed in Chronic Lobular Hepatitis B

Heoy Seung Kang, Hee Young Lee, Yoo Seok Kim, Ki Seub Lee, Byung ll Kim, Yun Chul Yie, Jung Ho Lee, Myeung Rae Lee, Dong ll Byun, Mi Yae Yoon, Soo Nam Lee

Department of Internal Medicine, Clinical Pathology, Anatomy Pathology, Incheon Christian Hospital, Incheon, Korea

Abstract

Although a pathogenic mechanism of hemolytic anemia complicated with viral hepatitis is unknown, it is suggested that there are four mechanisms; 1) In the individual who has predisposition to hemolytic anemia, virl infection accelerates the red cell destruction & hemolysis become obvious. 2) Directly, virus itself injures to the red cell membrane. 3) The serious liver failure & hypersplenism induce the hemolysis. 4) Autoimmune hemolytic anemia because of immunological abnormality caused by viral infection.
We experienced a case of autoimmune hemolytic anemia in 33-year-old male patient who was diagnosed as chronic lobular hepatitis B with biopsy.
Diagnosis was estabilished by clinical features, blood cell count, routine urinalysis, direct & indirect Coombs test, liver function test, immunoglobulin quantitations, hepatitis B marker, bone marrow aspiration, and liver biopsy. This case was treated with corticosteroid and transfusion. During follow-up, he has been well tolerated.

Keywords Autoimmune hemolytic anemia; Chronic lobular hepatitis;

Article

Korean J Hematol 1998; 33(2): 256-261

Published online June 30, 1998

Copyright © The Korean Society of Hematology.

만성 B형 간염환자에서 발생한 자가면역성 용혈성 빈혈 1례

강효승, 이희영, 김우석, 이기섭, 김병일, 여운철, 이정호, 이명래, 변동일, 윤미애, 이수남

인천기독병원 내과,
인천기독병원 임상병리과,
인천기독병원 해부병리과

A Case of Autoimmune Hemolytic Anemia Developed in Chronic Lobular Hepatitis B

Heoy Seung Kang, Hee Young Lee, Yoo Seok Kim, Ki Seub Lee, Byung ll Kim, Yun Chul Yie, Jung Ho Lee, Myeung Rae Lee, Dong ll Byun, Mi Yae Yoon, Soo Nam Lee

Department of Internal Medicine, Clinical Pathology, Anatomy Pathology, Incheon Christian Hospital, Incheon, Korea

Abstract

Although a pathogenic mechanism of hemolytic anemia complicated with viral hepatitis is unknown, it is suggested that there are four mechanisms; 1) In the individual who has predisposition to hemolytic anemia, virl infection accelerates the red cell destruction & hemolysis become obvious. 2) Directly, virus itself injures to the red cell membrane. 3) The serious liver failure & hypersplenism induce the hemolysis. 4) Autoimmune hemolytic anemia because of immunological abnormality caused by viral infection.
We experienced a case of autoimmune hemolytic anemia in 33-year-old male patient who was diagnosed as chronic lobular hepatitis B with biopsy.
Diagnosis was estabilished by clinical features, blood cell count, routine urinalysis, direct & indirect Coombs test, liver function test, immunoglobulin quantitations, hepatitis B marker, bone marrow aspiration, and liver biopsy. This case was treated with corticosteroid and transfusion. During follow-up, he has been well tolerated.

Keywords: Autoimmune hemolytic anemia, Chronic lobular hepatitis,

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