Korean J Hematol 2006; 41(2):
Published online June 30, 2006
https://doi.org/10.5045/kjh.2006.41.2.134
© The Korean Society of Hematology
권영란, 정재권, 김가영, 김새롬, 이세영, 윤영득, 이정림, 이원식, 권건영, 박재후
대구파티마병원 내과,
대구동산의료원 해부병리과,
울산대학교병원 내과
Cytomegalovirus (CMV) pneumonia is an important cause of treatment related mortality after allogeneic stem cell transplantation (SCT) and autologous SCT, particularly in a CD34 selected setting. There is little known about the immune reconstitution pertaining to the CMV after CD34 selected SCT. However, several studies have suggested there is more profound immunodeficiency early in the CD34 selected population compared with the unselected population. We encountered two fatal cases of CMV pneumonia at the CD34 selected SCT for T-cell lymphoblastic lymphoma and high-risk breast cancer that was confirmed through a lung biopsy and bronchoalveolar lavage. In conclusion, autologous CD34 selected CMV seropositive recipients need to be monitored in a similar manner to allogeneic recipients.
Keywords CMV pneumonia, CD34 selected stem cell transplantation, T-cell lymphoblastic lymphoma, Breast cancer
Korean J Hematol 2006; 41(2): 134-136
Published online June 30, 2006 https://doi.org/10.5045/kjh.2006.41.2.134
Copyright © The Korean Society of Hematology.
권영란, 정재권, 김가영, 김새롬, 이세영, 윤영득, 이정림, 이원식, 권건영, 박재후
대구파티마병원 내과,
대구동산의료원 해부병리과,
울산대학교병원 내과
Young Lan Kwon, Jae Kwon Joeng, Ga Young Kim, Sae Rom Kim, Se Young Lee, Young Deuk Youn, Jung Lim Lee, Won Sik Lee, Gun Young Kwon, Jae Hoo Park
Department of Internal Medicine, Daegu Fatima Hospital
Department of Pathology, Dongsan Medical Center,Deagu
Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea
Cytomegalovirus (CMV) pneumonia is an important cause of treatment related mortality after allogeneic stem cell transplantation (SCT) and autologous SCT, particularly in a CD34 selected setting. There is little known about the immune reconstitution pertaining to the CMV after CD34 selected SCT. However, several studies have suggested there is more profound immunodeficiency early in the CD34 selected population compared with the unselected population. We encountered two fatal cases of CMV pneumonia at the CD34 selected SCT for T-cell lymphoblastic lymphoma and high-risk breast cancer that was confirmed through a lung biopsy and bronchoalveolar lavage. In conclusion, autologous CD34 selected CMV seropositive recipients need to be monitored in a similar manner to allogeneic recipients.
Keywords: CMV pneumonia, CD34 selected stem cell transplantation, T-cell lymphoblastic lymphoma, Breast cancer
Hyoeun Shim, Hyun-Sook Chi, Seongsoo Jang, Eul-Ju Seo, Chan-Jeoung Park, Jung-Hee Lee, Je-Hwan Lee, and Kyoo-Hyung Lee
Korean J Hematol 2010; 45(3): 177-182