Korean J Hematol 2007; 42(2):
Published online June 30, 2007
https://doi.org/10.5045/kjh.2007.42.2.162
© The Korean Society of Hematology
김일두, 이승근, 이혜정, 조우성, 최영진, 신호진, 정주섭, 조군제, 이은엽
부산대학교 의학전문대학원 내과학교실, 진단검사의학교실
A 69-year-old female was referred to our institution due to abdominal pain and palpable purpura on both buttocks and legs. A skin biopsy of her purpura revealed granulocyte infiltration and leucocytoclasia around the arterioles and venuoles at the dermis, as well as an elevated serum immunoglobulin A level, hematuria and proteinuria. Therefore she was diagnosed with Henoch-Schönlein purpura. She had been diagnosed with diffuse large B cell lymphoma after a biopsy of her left inguinal lymph node 12 years ago and received 6 cycles of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) chemotherapy, which was followed by a complete remission. Abdominal and chest CT revealed multiple lymph node enlargement and bowel wall thickening at the ileocecal area, and lesions were observed in a whole body PET CT scan. Recurrence of the diffuse large B cell lymphoma was confirmed by a biopsy of the ileocecal area via colonoscopy. The purpura was improved after oral prednisolone therapy and etoposide, oxaliplatin and ifosfamide salvage combination chemotherapy was used to treat the lymphoma.
Keywords Henoch-Schönlein purpura, Diffuse large B cell lymphoma, Malignancy, Vasculitis
Korean J Hematol 2007; 42(2): 162-166
Published online June 30, 2007 https://doi.org/10.5045/kjh.2007.42.2.162
Copyright © The Korean Society of Hematology.
김일두, 이승근, 이혜정, 조우성, 최영진, 신호진, 정주섭, 조군제, 이은엽
부산대학교 의학전문대학원 내과학교실, 진단검사의학교실
Il Du Kim, Seung Geun Lee, Hye Jeong Lee, Woo Sung Jo, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Goon Jae Cho, Eun Yup Lee
Departments of Internal Medicine and, Laboratory Medicine, School of Medicine, Pusan National University, Busan, Korea
A 69-year-old female was referred to our institution due to abdominal pain and palpable purpura on both buttocks and legs. A skin biopsy of her purpura revealed granulocyte infiltration and leucocytoclasia around the arterioles and venuoles at the dermis, as well as an elevated serum immunoglobulin A level, hematuria and proteinuria. Therefore she was diagnosed with Henoch-Schönlein purpura. She had been diagnosed with diffuse large B cell lymphoma after a biopsy of her left inguinal lymph node 12 years ago and received 6 cycles of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) chemotherapy, which was followed by a complete remission. Abdominal and chest CT revealed multiple lymph node enlargement and bowel wall thickening at the ileocecal area, and lesions were observed in a whole body PET CT scan. Recurrence of the diffuse large B cell lymphoma was confirmed by a biopsy of the ileocecal area via colonoscopy. The purpura was improved after oral prednisolone therapy and etoposide, oxaliplatin and ifosfamide salvage combination chemotherapy was used to treat the lymphoma.
Keywords: Henoch-Schö,nlein purpura, Diffuse large B cell lymphoma, Malignancy, Vasculitis
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