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Korean J Hematol 2012; 47(4):
Published online December 31, 2012
https://doi.org/10.5045/kjh.2012.47.4.307
© The Korean Society of Hematology
Molecular methods for genomic analyses of variant PML-RARA or other RARA -related chromosomal translocations in acute promyelocytic leukemia
1Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
2Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-702, Korea.
3Institute of Pharmaceutical Biology, ZAFES, Diagnostic Center of Acute Leukemia, Goethe-University of Frankfurt, Biocenter, Frankfurt/Main, Germany.
Correspondence to : Correspondence to Tae Sung Park, M.D., Ph.D. Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-702, Korea. Tel: +82-2-958-8673, 53jesus@hanmail.net
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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REFERENCES
- Palta, A, Dhiman, P, Cruz, SD. ZBTB16-RARα variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature. Korean J Hematol, 2012;47;229-232.
- Kang, LC, Smith, SV, Kaiser-Rogers, K, Rao, K, Dunphy, CH. Two cases of acute myeloid leukemia with t(11;17) associated with varying morphology and immunophenotype: rearrangement of the MLL gene and a region proximal to the RARalpha gene. Cancer Genet Cytogenet, 2005;159;168-173.
- Yang, JJ, Marschalek, R, Meyer, C, Park, TS. Diagnostic usefulness of genomic breakpoint analysis of various gene rearrangements in acute leukemias: a perspective of long distance- or long distance inverse-PCR-based approaches. Ann Lab Med, 2012;32;316-318.
- Lim, G, Cho, EH, Cho, SY, et al. A novel PML-ADAMTS17-RARA gene rearrangement in a patient with pregnancy-related acute promyelocytic leukemia. Leuk Res, 2011;35;e106-e110.
- Yang, JJ, Park, TS, Kim, MJ, et al. Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in molecularly discrepant leukemia cases. Ann Hematol, 2012;91;1645-1648.
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Letter to the Editor
Korean J Hematol 2012; 47(4): 307-308
Published online December 31, 2012 https://doi.org/10.5045/kjh.2012.47.4.307
Copyright © The Korean Society of Hematology.
Molecular methods for genomic analyses of variant PML-RARA or other RARA -related chromosomal translocations in acute promyelocytic leukemia
Min Jin Kim, M.D.1, John Jeongseok Yang, M.D.2, Claus Meyer, Ph.D.3, Rolf Marschalek, Ph.D.3, and Tae Sung Park, M.D. Ph.D.2*
1Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
2Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-702, Korea.
3Institute of Pharmaceutical Biology, ZAFES, Diagnostic Center of Acute Leukemia, Goethe-University of Frankfurt, Biocenter, Frankfurt/Main, Germany.
Correspondence to: Correspondence to Tae Sung Park, M.D., Ph.D. Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-702, Korea. Tel: +82-2-958-8673, 53jesus@hanmail.net
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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References
- Palta, A, Dhiman, P, Cruz, SD. ZBTB16-RARα variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature. Korean J Hematol, 2012;47;229-232.
- Kang, LC, Smith, SV, Kaiser-Rogers, K, Rao, K, Dunphy, CH. Two cases of acute myeloid leukemia with t(11;17) associated with varying morphology and immunophenotype: rearrangement of the MLL gene and a region proximal to the RARalpha gene. Cancer Genet Cytogenet, 2005;159;168-173.
- Yang, JJ, Marschalek, R, Meyer, C, Park, TS. Diagnostic usefulness of genomic breakpoint analysis of various gene rearrangements in acute leukemias: a perspective of long distance- or long distance inverse-PCR-based approaches. Ann Lab Med, 2012;32;316-318.
- Lim, G, Cho, EH, Cho, SY, et al. A novel PML-ADAMTS17-RARA gene rearrangement in a patient with pregnancy-related acute promyelocytic leukemia. Leuk Res, 2011;35;e106-e110.
- Yang, JJ, Park, TS, Kim, MJ, et al. Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in molecularly discrepant leukemia cases. Ann Hematol, 2012;91;1645-1648.
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