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Korean J Hematol 2012; 47(4):

Published online December 31, 2012

https://doi.org/10.5045/kjh.2012.47.4.309

© The Korean Society of Hematology

Long-term survival of a patient with bone marrow gelatinous degeneration of idiopathic origin

Pasquale Niscola, M.D.1*, Massimiliano Palombi, M.D.1, Stefano Fratoni, M.D.2, Malgorzata Monika Trawinska, M.D.1, Laura Scaramucci, M.D.1, Andrea Tendas, M.D.1, Marco Giovannini, M.D.1, Alessio Perrotti, M.D.1, and Paolo de Fabritiis, M.D.1

Author Info. +

1Haematology Department, Sant' Eugenio Hospital, Piazzale dell' Umanesimo 10, 00144 Rome, Italy.

2Pathology Department, Sant' Eugenio Hospital, Piazzale dell' Umanesimo 10, 00144 Rome, Italy.

Correspondence to : Correspondence to Pasquale Niscola, M.D. Haematology Department, Sant' Eugenio Hospital, Piazzale dell' Umanesimo 10, 00144 Rome, Italy. Tel: +390651003241, pniscola@gmail.com

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

FIGURES

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Fig. 1.

Serous atrophy in a diffuse and severe hypocellular background (A). Reduced fat cells, a diffuse extracellular gelatinous amorphous material, small typical lymphocytes, and mature plasma cells were also observed (B). Small islets of hematopoietic cells were detected at a level of <5%.


REFERENCES

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  1. Böhm, J. Gelatinous transformation of the bone marrow: the spectrum of underlying diseases. Am J Surg Pathol, 2000;24;56-65.
    Pubmed
  2. Aisa, Y, Mori, T, Nakazato, T, Yamazaki, R, Ikeda, Y, Okamoto, S. Gelatinous degeneration in a recipient of allogeneic bone marrow transplantation. Int J Hematol, 2006;84;465-467.
    Pubmed
  3. Arranz, R, Gil-Fernandez, JJ, Acevedo, A, Tomas, JF, Alegre, A, Fernandez-Rañada, JM. Gelatinous degeneration presenting as a preleukaemic syndrome. J Clin Pathol, 1996;49;512-514.
    Pubmed
  4. Böhm, J, Schmitt-Gräff, A. Gelatinous bone marrow transformation in a case of idiopathic myelofibrosis: a morphological paradox. Pathol Res Pract, 2000;196;775-779.
    Pubmed
  5. Niscola, P, Maurillo, L, Palombi, M, et al. Gelatinous degeneration of the bone marrow: two case reports showing different hematological features and clinical outcomes. Acta Haematol, 2007;118;165-166.
    Pubmed

Article

Letter to the Editor

Korean J Hematol 2012; 47(4): 309-310

Published online December 31, 2012 https://doi.org/10.5045/kjh.2012.47.4.309

Copyright © The Korean Society of Hematology.

Long-term survival of a patient with bone marrow gelatinous degeneration of idiopathic origin

Pasquale Niscola, M.D.1*, Massimiliano Palombi, M.D.1, Stefano Fratoni, M.D.2, Malgorzata Monika Trawinska, M.D.1, Laura Scaramucci, M.D.1, Andrea Tendas, M.D.1, Marco Giovannini, M.D.1, Alessio Perrotti, M.D.1, and Paolo de Fabritiis, M.D.1

1Haematology Department, Sant' Eugenio Hospital, Piazzale dell' Umanesimo 10, 00144 Rome, Italy.

2Pathology Department, Sant' Eugenio Hospital, Piazzale dell' Umanesimo 10, 00144 Rome, Italy.

Correspondence to: Correspondence to Pasquale Niscola, M.D. Haematology Department, Sant' Eugenio Hospital, Piazzale dell' Umanesimo 10, 00144 Rome, Italy. Tel: +390651003241, pniscola@gmail.com

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Fig 1.

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    Figure 1.

    Serous atrophy in a diffuse and severe hypocellular background (A). Reduced fat cells, a diffuse extracellular gelatinous amorphous material, small typical lymphocytes, and mature plasma cells were also observed (B). Small islets of hematopoietic cells were detected at a level of <5%.

    Blood Research 2012; 47: 309-310https://doi.org/10.5045/kjh.2012.47.4.309

    References

    1. Böhm, J. Gelatinous transformation of the bone marrow: the spectrum of underlying diseases. Am J Surg Pathol, 2000;24;56-65.
      Pubmed
    2. Aisa, Y, Mori, T, Nakazato, T, Yamazaki, R, Ikeda, Y, Okamoto, S. Gelatinous degeneration in a recipient of allogeneic bone marrow transplantation. Int J Hematol, 2006;84;465-467.
      Pubmed
    3. Arranz, R, Gil-Fernandez, JJ, Acevedo, A, Tomas, JF, Alegre, A, Fernandez-Rañada, JM. Gelatinous degeneration presenting as a preleukaemic syndrome. J Clin Pathol, 1996;49;512-514.
      Pubmed
    4. Böhm, J, Schmitt-Gräff, A. Gelatinous bone marrow transformation in a case of idiopathic myelofibrosis: a morphological paradox. Pathol Res Pract, 2000;196;775-779.
      Pubmed
    5. Niscola, P, Maurillo, L, Palombi, M, et al. Gelatinous degeneration of the bone marrow: two case reports showing different hematological features and clinical outcomes. Acta Haematol, 2007;118;165-166.
      Pubmed
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