Blood Res 2021; 56(4):
Published online December 31, 2021
https://doi.org/10.5045/br.2021.2021128
© The Korean Society of Hematology
Correspondence to : Govinda Khatri
Department of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Sindh 75500, Pakistan
E-mail: govindakhatri550@gmail.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
TO THE EDITOR: We have read the article entitled “Molecular basis and diagnosis of thalassemia” by Farashi and Harteveld that was recently published in
The authors described the molecular underpinnings of alpha and beta thalassemia separately in this article. Every facet of the illnesses was addressed, including diagnostic criteria for both, yet there was no mention of their common molecular basis or co-inheritance.
We would like to emphasize this issue by pointing out that other published manuscripts have reported on both types of thalassemia. In a study in Pakistan, in order to establish the prevalence and investigate the spectra of alpha thalassemia gene deletions in patients with beta thalassemia, Shahid
The co-inheritance of alpha and beta thalassemia is quite rare; according to Li
These findings imply that a diagnostic criterion for screening patients with concurrent alpha and beta thalassemia should be developed. Furthermore, prenatal testing and genetic counseling should be undertaken in regions where alpha and beta thalassemia are more common in order to build a controlled and preventative environment that could lead to a lower incidence of co-inheritance of the two diseases.
No potential conflicts of interest relevant to this article were reported.
Blood Res 2021; 56(4): 332-333
Published online December 31, 2021 https://doi.org/10.5045/br.2021.2021128
Copyright © The Korean Society of Hematology.
Govinda Khatri, Abdul Moiz Sahito, Saboor Ahmed Ansari
Department of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
Correspondence to:Govinda Khatri
Department of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Sindh 75500, Pakistan
E-mail: govindakhatri550@gmail.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
TO THE EDITOR: We have read the article entitled “Molecular basis and diagnosis of thalassemia” by Farashi and Harteveld that was recently published in
The authors described the molecular underpinnings of alpha and beta thalassemia separately in this article. Every facet of the illnesses was addressed, including diagnostic criteria for both, yet there was no mention of their common molecular basis or co-inheritance.
We would like to emphasize this issue by pointing out that other published manuscripts have reported on both types of thalassemia. In a study in Pakistan, in order to establish the prevalence and investigate the spectra of alpha thalassemia gene deletions in patients with beta thalassemia, Shahid
The co-inheritance of alpha and beta thalassemia is quite rare; according to Li
These findings imply that a diagnostic criterion for screening patients with concurrent alpha and beta thalassemia should be developed. Furthermore, prenatal testing and genetic counseling should be undertaken in regions where alpha and beta thalassemia are more common in order to build a controlled and preventative environment that could lead to a lower incidence of co-inheritance of the two diseases.
No potential conflicts of interest relevant to this article were reported.