
1Laboratoire d'Hématologie Biologique, Groupement Hospitalier Lyon-Sud/Hospices Civils de Lyon, Lyon, France.
2Service d'Anatomie Pathologique, Groupement Hospitalier Lyon-Sud/Hospices Civils de Lyon, Lyon, France.
3Service d'Hématologie Clinique, Groupement Hospitalier Lyon-Sud/Hospices Civils de Lyon, Lyon, France.
4Service d'Anatomie Pathologique, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
A 73-year-old woman with bilateral breast implants following mastectomies for cancer and a previous right-sided implant revision due to implant rupture presented to us with ultrasound-confirmed fluid accumulation around the left implant, without lymphadenopathy, splenomegaly, or B symptoms.
Cytological analysis of the seroma fluid (
BIA-ALCL, recently recognized in the 2016 World Health Organization Classification of Lymphomas, is often curable when diagnosed early. As recommended by the National Comprehensive Cancer Network (NCCN) guidelines, appropriate cytological examination of seroma fluid utilizing FCM and IHC, including CD30 and ALK staining, appears crucial to its diagnosis.