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Letter to the Editor

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Blood Res 2016; 51(1):

Published online March 31, 2016

https://doi.org/10.5045/br.2016.51.1.67

© The Korean Society of Hematology

Combined factor V and VIII deficiency in a young woman with abundant bleeding after tooth extraction

Ihsan Ates1*, Mustafa Kaplan1, Gul Tokgoz2, Funda Ceran2, Simten Akalın2, and Gulsum Ozet2

Author Info. +

1Internal Medicine Department, Ankara Numune Training and Research Hospital, Ankara, Turkey.

2Hematology Department, Ankara Numune Training and Research Hospital, Ankara, Turkey.

Correspondence to : Ihsan Ates. Department of Internal Medicine, Ankara Numune Training and Research Hospital, 06100, Sıhhiye, Ankara, Turkey. dr.ihsanates@hotmail.com

Received: February 15, 2015; Revised: May 11, 2015; Accepted: June 9, 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

TABLES

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Table. 1.

Table 1 Hemostatic parameters.

Abbreviations: aPTT, activated partial prothrombin time; PT, prothrombin time; INR, international normalized ratio; vWF, von Willebrand factor.

REFERENCES

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  1. Oeri, J, Matter, M, Isenschmid, H, Hauser, F, Koller, F. Congenital factor V deficiency (parahemophilia) with true hemophilia in two brothers. Bibl Paediatr, 1954;58;575-588.
    Pubmed
  2. Mansouritorgabeh, H, Rezaieyazdi, Z, Pourfathollah, AA, Rezai, J, Esamaili, H. Haemorrhagic symptoms in patients with combined factors V and VIII deficiency in north-eastern Iran. Haemophilia, 2004;10;271-275.
    Pubmed
  3. Sirachainan, N, Zhang, B, Chuansumrit, A, Pipe, S, Sasanakul, W, Ginsburg, D. Combined factor V and factor VIII deficiency in a Thai patient: a case report of genotype and phenotype characteristics. Haemophilia, 2005;11;280-284.
    Pubmed
  4. Spreafico, M, Peyvandi, F. Combined factor V and factor VIII deficiency. Semin Thromb Hemost, 2009;35;390-399.
    Pubmed
  5. Seligsohn, U, Zivelin, A, Zwang, E. Combined factor V and factor VIII deficiency among non-Ashkenazi Jews. N Engl J Med, 1982;307;1191-1195.
    Pubmed
  6. Giddings, JC, Seligsohn, U, Bloom, AL. Immunological studies in combined factor V and factor VIII deficiency. Br J Haematol, 1977;37;257-264.
    Pubmed
  7. Nichols, WC, Seligsohn, U, Zivelin, A, et al. Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII. Cell, 1998;93;61-70.
    Pubmed
  8. Peyvandi, F, Tuddenham, EG, Akhtari, AM, Lak, M, Mannucci, PM. Bleeding symptoms in 27 Iranian patients with the combined deficiency of factor V and factor VIII. Br J Haematol, 1998;100;773-776.
    Pubmed
  9. Mannucci, PM, Duga, S, Peyvandi, F. Recessively inherited coagulation disorders. Blood, 2004;104;1243-1252.
    Pubmed
  10. Spreafico, M, Peyvandi, F. Combined FV and FVIII deficiency. Haemophilia, 2008;14;1201-1208.
    Pubmed

Article

Letter to the Editor

Blood Res 2016; 51(1): 67-68

Published online March 31, 2016 https://doi.org/10.5045/br.2016.51.1.67

Copyright © The Korean Society of Hematology.

Combined factor V and VIII deficiency in a young woman with abundant bleeding after tooth extraction

Ihsan Ates1*, Mustafa Kaplan1, Gul Tokgoz2, Funda Ceran2, Simten Akalın2, and Gulsum Ozet2

1Internal Medicine Department, Ankara Numune Training and Research Hospital, Ankara, Turkey.

2Hematology Department, Ankara Numune Training and Research Hospital, Ankara, Turkey.

Correspondence to: Ihsan Ates. Department of Internal Medicine, Ankara Numune Training and Research Hospital, 06100, Sıhhiye, Ankara, Turkey. dr.ihsanates@hotmail.com

Received: February 15, 2015; Revised: May 11, 2015; Accepted: June 9, 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Table 1 . Hemostatic parameters..

    Abbreviations: aPTT, activated partial prothrombin time; PT, prothrombin time; INR, international normalized ratio; vWF, von Willebrand factor..

    References

    1. Oeri, J, Matter, M, Isenschmid, H, Hauser, F, Koller, F. Congenital factor V deficiency (parahemophilia) with true hemophilia in two brothers. Bibl Paediatr, 1954;58;575-588.
      Pubmed
    2. Mansouritorgabeh, H, Rezaieyazdi, Z, Pourfathollah, AA, Rezai, J, Esamaili, H. Haemorrhagic symptoms in patients with combined factors V and VIII deficiency in north-eastern Iran. Haemophilia, 2004;10;271-275.
      Pubmed
    3. Sirachainan, N, Zhang, B, Chuansumrit, A, Pipe, S, Sasanakul, W, Ginsburg, D. Combined factor V and factor VIII deficiency in a Thai patient: a case report of genotype and phenotype characteristics. Haemophilia, 2005;11;280-284.
      Pubmed
    4. Spreafico, M, Peyvandi, F. Combined factor V and factor VIII deficiency. Semin Thromb Hemost, 2009;35;390-399.
      Pubmed
    5. Seligsohn, U, Zivelin, A, Zwang, E. Combined factor V and factor VIII deficiency among non-Ashkenazi Jews. N Engl J Med, 1982;307;1191-1195.
      Pubmed
    6. Giddings, JC, Seligsohn, U, Bloom, AL. Immunological studies in combined factor V and factor VIII deficiency. Br J Haematol, 1977;37;257-264.
      Pubmed
    7. Nichols, WC, Seligsohn, U, Zivelin, A, et al. Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII. Cell, 1998;93;61-70.
      Pubmed
    8. Peyvandi, F, Tuddenham, EG, Akhtari, AM, Lak, M, Mannucci, PM. Bleeding symptoms in 27 Iranian patients with the combined deficiency of factor V and factor VIII. Br J Haematol, 1998;100;773-776.
      Pubmed
    9. Mannucci, PM, Duga, S, Peyvandi, F. Recessively inherited coagulation disorders. Blood, 2004;104;1243-1252.
      Pubmed
    10. Spreafico, M, Peyvandi, F. Combined FV and FVIII deficiency. Haemophilia, 2008;14;1201-1208.
      Pubmed
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