Case Report
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Blood Res 2014; 49(2):
Published online June 25, 2014
https://doi.org/10.5045/br.2014.49.2.127
© The Korean Society of Hematology
A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Correspondence to : Correspondence to Byeong-Bae Park, M.D. Department of Internal Medicine, Hanyang University College of Medicine, 222, Wangsimni-ro, Seongdong-gu, Seoul 133-791, Korea. Tel: +82-2-2290-8335, Fax: +82-2-2298-9183, bbpark@hanyang.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by overproduction of myeloid white blood cells. Philadelphia chromosome is an essential finding for CML diagnosis. Generally, a clinical diagnosis of essential thrombocythemia (ET) can be established from isolated marked thrombocytosis in peripheral blood. However, Philadelphia chromosome-positivity or
Keywords Chronic myeloid leukemia, Philadelphia chromosome, Essential thrombocythemia
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Case Report
Blood Res 2014; 49(2): 127-129
Published online June 25, 2014 https://doi.org/10.5045/br.2014.49.2.127
Copyright © The Korean Society of Hematology.
A case of chronic myeloid leukemia with features of essential thrombocythemia in peripheral blood and bone marrow
Young Jae Byun, Byeong-Bae Park*, Eun Sung Lee, Kyung Soo Choi, and Dae Sung Lee
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Correspondence to: Correspondence to Byeong-Bae Park, M.D. Department of Internal Medicine, Hanyang University College of Medicine, 222, Wangsimni-ro, Seongdong-gu, Seoul 133-791, Korea. Tel: +82-2-2290-8335, Fax: +82-2-2298-9183, bbpark@hanyang.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by overproduction of myeloid white blood cells. Philadelphia chromosome is an essential finding for CML diagnosis. Generally, a clinical diagnosis of essential thrombocythemia (ET) can be established from isolated marked thrombocytosis in peripheral blood. However, Philadelphia chromosome-positivity or
Keywords: Chronic myeloid leukemia, Philadelphia chromosome, Essential thrombocythemia
Fig 1.
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Thrombocytosis without obvious morphologic abnormalities of the white blood cells and erythrocytes in peripheral blood smear (Wright Giemsa stain, ×400).
Fig 2.
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Bone marrow core biopsy sample showing hypercellular bone marrow for age with expanded myelopoiesis and small megakaryocytes with decreased nuclear lobation (H&E stain, ×200).
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