Korean J Hematol 2001; 36(2):
Published online June 30, 2001
© The Korean Society of Hematology
위망상적혈구증가증이 동반된 골수이형성증후군 1례
강진욱, 이지석, 김지영, 김상현, 박찬원, 정영태, 정주섭, 조군제, 박태성, 이은엽
부산대학교 의과대학 내과학교실,
부산대학교 의과대학 임상병리학교실
Pseudoreticulocytosis in a Case of Myelodysplastic Syndrome
Myelodysplastic syndrome (MDS) is a group of hematopoietic disorders characterized by ineffective hematopoiesis and peripheral cytopenia associated with dysplastic hypercellular marrow. Anemia is a frequent finding and reticulocytes are usually normal or slightly decreased in the patients with MDS. 'Pseudoreticulocytosis' is a rare abnormality of patients with MDS. In these patients, the delayed maturation of reticulocytes is revealed and unusual reticulocytosis occurs with the decreased red cell
production. We report a case of MDS characterized by the anemia associated with high reticulocyte count. 'In vitro reticulocyte survival test' showed that the reticulocytosis was a consequence of delayed maturation.
Keywords Myelodysplastic syndrome, Pseudoreticulocytosis
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Korean J Hematol 2001; 36(2): 176-179
Published online June 30, 2001
Copyright © The Korean Society of Hematology.
위망상적혈구증가증이 동반된 골수이형성증후군 1례
강진욱, 이지석, 김지영, 김상현, 박찬원, 정영태, 정주섭, 조군제, 박태성, 이은엽
부산대학교 의과대학 내과학교실,
부산대학교 의과대학 임상병리학교실
Pseudoreticulocytosis in a Case of Myelodysplastic Syndrome
Jin Ouk Kang, Ji Seuk Lee, Ji Young Kim, Sang Hyun Kim, Chan Won Park, Yeong Tae Jeong, Joo Seop Chung, Goon Jae Cho, Tae Sung Park, Eun Yup Lee
Department of Internal Medicine, Clinical Pathology, College of Medicine, Pusan National University, Pusan, Korea
Abstract
Myelodysplastic syndrome (MDS) is a group of hematopoietic disorders characterized by ineffective hematopoiesis and peripheral cytopenia associated with dysplastic hypercellular marrow. Anemia is a frequent finding and reticulocytes are usually normal or slightly decreased in the patients with MDS. 'Pseudoreticulocytosis' is a rare abnormality of patients with MDS. In these patients, the delayed maturation of reticulocytes is revealed and unusual reticulocytosis occurs with the decreased red cell
production. We report a case of MDS characterized by the anemia associated with high reticulocyte count. 'In vitro reticulocyte survival test' showed that the reticulocytosis was a consequence of delayed maturation.
Keywords: Myelodysplastic syndrome, Pseudoreticulocytosis
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