Korean J Hematol 1990; 25(2):
Published online June 30, 1990
© The Korean Society of Hematology
특발성 혈소판감소성 자반증에서의 Vitamin C의 치료효과
정병천, 김광원, 신동건, 손상균, 이재태, 이규보, 황기석
경북대학교 의과대학 내과학교실
Therapeutic Effect of Vitamin C for Idiopathic Thrombocytopenic Purpura
The authors evaluated the therapeutic efficacy of vitamin C for 21 adult patients of idiopathic thrombocytopenic purpura. The subject was composed of 20 females and one
male from the age ranges between 17 and 72 years.
The administration of vitamin C was 2.0gm per day to the patients as both a single therapy for 4 patients and a combination therapy with other regimens for 17. Among the
total patients, five cases became complete remission(23.8%), two cases were partial remission(9.5%), three cases obtained sustainable therapeutic status of previous
regimen(14.2%), and eleven cases were nonresponders(52.4%). However, two out of 4 cases of single therapy group showed complete remission (50.0%). The periods from start of medication to effective response were varied from 1 week to 6 months. There were no remarkable side reactions of vitamin C therapy.
Keywords Vitamin C; Idiopathic thrombocytopenic purpura;
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Korean J Hematol 1990; 25(2): 439-445
Published online June 30, 1990
Copyright © The Korean Society of Hematology.
특발성 혈소판감소성 자반증에서의 Vitamin C의 치료효과
정병천, 김광원, 신동건, 손상균, 이재태, 이규보, 황기석
경북대학교 의과대학 내과학교실
Therapeutic Effect of Vitamin C for Idiopathic Thrombocytopenic Purpura
Byung Cheon Jeong, Kwang Weon Kim, Dong Gun Shin, Sang Kyun Sohn, Jae Tae Lee, Kyu Bo Lee, Kee Suk Whang
Department of Internal Medicine, School of Medicine, Kyungpook National University, Taegu, Korea
Abstract
The authors evaluated the therapeutic efficacy of vitamin C for 21 adult patients of idiopathic thrombocytopenic purpura. The subject was composed of 20 females and one
male from the age ranges between 17 and 72 years.
The administration of vitamin C was 2.0gm per day to the patients as both a single therapy for 4 patients and a combination therapy with other regimens for 17. Among the
total patients, five cases became complete remission(23.8%), two cases were partial remission(9.5%), three cases obtained sustainable therapeutic status of previous
regimen(14.2%), and eleven cases were nonresponders(52.4%). However, two out of 4 cases of single therapy group showed complete remission (50.0%). The periods from start of medication to effective response were varied from 1 week to 6 months. There were no remarkable side reactions of vitamin C therapy.
Keywords: Vitamin C, Idiopathic thrombocytopenic purpura,
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