Korean J Hematol 2010; 45(2):
Published online June 30, 2010
https://doi.org/10.5045/kjh.2010.45.2.127
© The Korean Society of Hematology
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
Correspondence to : Correspondence to Ho Sup Lee, M.D. Division of Hematology/Oncology, Department of Internal Medicine, Kosin University College of Medicine, 34, Amnam-dong, Seo-gu, Busan 602-703, Korea. Tel: +82-51-990-6107, Fax: +82-51-990-5820, hs3667@hanmail.net
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The relationship between
A total of 25 patients (18 male, 7 female; the median age of 55 years) diagnosed with ITP, whose platelet counts were less than 100×103/µL, were enrolled. They were tested for
Of the 25 patients, 23 (92%) were diagnosed with
This study confirmed the efficacy of
Keywords
Until now, there have been many studies on the relationship between
In this retrospective study of patients with chronic ITP and
The medical records of 25 adult chronic ITP patients, seen at Kosin University Gospel Hospital in Busan, South Korea, between June 1996 and November 2009, were retrospectively examined for the presence of gastric
All 25 patients were screened for
Platelet counts were assessed when patients reached remission after
The clinical response to treatment was defined by the International Working Group on ITP [22]. Complete response (CR) was defined as a platelet count of at least 100×103/µL for more than 2 months with or without maintenance therapy. Partial response (PR) was defined as a platelet count of at least 30×103/µL and at least doubling the baseline count over a period of more than 2 months. No response (NR) was defined as a platelet count below 30×103/µL, or when the platelet count did not increase to more than 50% of the pretreatment level with or without maintenance therapy.
Data are expressed as the median (range) as appropriate. The following variables were analyzed to identify factors associated with the improvement in the platelet count after eradication therapy: age, sex, disease duration,
Background characteristics of the patients with ITP are indicated in Table 1. The median age was 55 years (range: 35-76 years), 18 were men (7 women), and the median platelet count was 78×103/µL (range: 6-96×103/µL). The median follow-up duration of this study was 57.57 months (range: 4.53-123.53 months). Twenty-three patients had histologically confirmed
Outcomes after
Predictors of response to
Many studies have shown an association between
Gasbarrini et al. first reported that patients in whom
In contrast to our study, an Italian report by Stasi et al. concluded that
The platelet recovery rate after
In conclusion, the eradication of
Response duration after
Individual changes of platelet counts in responsive, non-responsive and relapsed patients with complete
Table 1 Patients characteristics.
The values represent either the number (percentage) or the median (range).
Abbreviations:
Table 2 Outcomes after
The values represent either the number (percentage) or the median (range).
Abbreviations:
Table 3 Comparison of the patients characteristics between responders and non-responders.
The values represent either the number (percentage) or the mean±SD.
Abbreviations:
Korean J Hematol 2010; 45(2): 127-132
Published online June 30, 2010 https://doi.org/10.5045/kjh.2010.45.2.127
Copyright © The Korean Society of Hematology.
Hee Sang Tag, Ho Sup Lee*, Su-Hyeon Jung, Bu-Kyung Kim, Sung-Bin Kim, Aeran Lee, Jin Soo Lee, Seong Hoon Shin, and Yang Soo Kim
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
Correspondence to: Correspondence to Ho Sup Lee, M.D. Division of Hematology/Oncology, Department of Internal Medicine, Kosin University College of Medicine, 34, Amnam-dong, Seo-gu, Busan 602-703, Korea. Tel: +82-51-990-6107, Fax: +82-51-990-5820, hs3667@hanmail.net
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The relationship between
A total of 25 patients (18 male, 7 female; the median age of 55 years) diagnosed with ITP, whose platelet counts were less than 100×103/µL, were enrolled. They were tested for
Of the 25 patients, 23 (92%) were diagnosed with
This study confirmed the efficacy of
Keywords:
Until now, there have been many studies on the relationship between
In this retrospective study of patients with chronic ITP and
The medical records of 25 adult chronic ITP patients, seen at Kosin University Gospel Hospital in Busan, South Korea, between June 1996 and November 2009, were retrospectively examined for the presence of gastric
All 25 patients were screened for
Platelet counts were assessed when patients reached remission after
The clinical response to treatment was defined by the International Working Group on ITP [22]. Complete response (CR) was defined as a platelet count of at least 100×103/µL for more than 2 months with or without maintenance therapy. Partial response (PR) was defined as a platelet count of at least 30×103/µL and at least doubling the baseline count over a period of more than 2 months. No response (NR) was defined as a platelet count below 30×103/µL, or when the platelet count did not increase to more than 50% of the pretreatment level with or without maintenance therapy.
Data are expressed as the median (range) as appropriate. The following variables were analyzed to identify factors associated with the improvement in the platelet count after eradication therapy: age, sex, disease duration,
Background characteristics of the patients with ITP are indicated in Table 1. The median age was 55 years (range: 35-76 years), 18 were men (7 women), and the median platelet count was 78×103/µL (range: 6-96×103/µL). The median follow-up duration of this study was 57.57 months (range: 4.53-123.53 months). Twenty-three patients had histologically confirmed
Outcomes after
Predictors of response to
Many studies have shown an association between
Gasbarrini et al. first reported that patients in whom
In contrast to our study, an Italian report by Stasi et al. concluded that
The platelet recovery rate after
In conclusion, the eradication of
Response duration after
Individual changes of platelet counts in responsive, non-responsive and relapsed patients with complete
Table 1 . Patients characteristics..
The values represent either the number (percentage) or the median (range)..
Abbreviations:
Table 2 . Outcomes after
The values represent either the number (percentage) or the median (range)..
Abbreviations:
Table 3 . Comparison of the patients characteristics between responders and non-responders..
The values represent either the number (percentage) or the mean±SD..
Abbreviations:
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Response duration after
Individual changes of platelet counts in responsive, non-responsive and relapsed patients with complete