Korean J Hematol 2009; 44(1):
Published online March 30, 2009
https://doi.org/10.5045/kjh.2009.44.1.58
© The Korean Society of Hematology
김형수 김정한 나동길 장대영 박민정 김홍배 이종욱
한림대 의과대학 산부인과학교실, 내과학교실
가톨릭대 의과대학 내과학교실,혈액과
We describe here the case a patient with advanced cervix carcinoma and who developed idiopathic thrombocytopenic purpura (ITP). A 63-year-old woman with stage IV squamous cell carcinoma of the uterine cervix and that was complicated by hydronephrosis was treated palliatively with 45Gy of external beam radiation to the pelvis. About 3 years later, she developed hematochezia and severe thrombocytopenia. The laboratory examinations showed no evidence of thrombotic thrombocytopenic purpura or disseminated intravascular coagulopathy, and she was positive for serum anti-platelet antibodies. On the bone marrow examination, there was a normal number and morphology of megakaryocytes with no evidence of malignant cell infiltration. We made the clinical diagnosis of ITP, and the intravenous immunoglobulin and steroid therapy was successful. This case suggests the possibility that ITP can occur in association with advanced cervix carcinoma.
Keywords Autoimmune thrombocytopena, Idiopathic thrombocytopenic purpura, Cervix carcinoma
Korean J Hematol 2009; 44(1): 58-60
Published online March 30, 2009 https://doi.org/10.5045/kjh.2009.44.1.58
Copyright © The Korean Society of Hematology.
김형수 김정한 나동길 장대영 박민정 김홍배 이종욱
한림대 의과대학 산부인과학교실, 내과학교실
가톨릭대 의과대학 내과학교실,혈액과
Hyeong Su Kim, Jung Han Kim, Dong Kil Na, Dae Young Zang, Min Jeong Park, Hong Bae Kim, Jong Wook Lee
Departments of Internal Medicine, Laboratory Medicine, and Gynecology, Hallym University Medical Center, Hallym University College of Medicine, Division of Hematology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
We describe here the case a patient with advanced cervix carcinoma and who developed idiopathic thrombocytopenic purpura (ITP). A 63-year-old woman with stage IV squamous cell carcinoma of the uterine cervix and that was complicated by hydronephrosis was treated palliatively with 45Gy of external beam radiation to the pelvis. About 3 years later, she developed hematochezia and severe thrombocytopenia. The laboratory examinations showed no evidence of thrombotic thrombocytopenic purpura or disseminated intravascular coagulopathy, and she was positive for serum anti-platelet antibodies. On the bone marrow examination, there was a normal number and morphology of megakaryocytes with no evidence of malignant cell infiltration. We made the clinical diagnosis of ITP, and the intravenous immunoglobulin and steroid therapy was successful. This case suggests the possibility that ITP can occur in association with advanced cervix carcinoma.
Keywords: Autoimmune thrombocytopena, Idiopathic thrombocytopenic purpura, Cervix carcinoma
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