Korean J Hematol 1999; 34(3):
Published online September 30, 1999
© The Korean Society of Hematology
대뇌를 침범하고 거대 두개형질세포종을 동반한 다발성골수종 1례
김범준, 한지연, 김태균, 이경식, 안재근, 지철, 이강훈, 김현숙
가톨릭대학교 의과대학 내과학교실,
가톨릭대학교 의과대학 신경외과학교실,
가톨릭대학교 의과대학 방사선과학교실
A Case of Multiple Myeloma Presented with a Bulky Cranial Plasmacytoma Invading Cerebrum
Although neurologic complications of multiple myeloma are common, brain-involvement is rare, despite the high frequency of the cranial lesions. The cranial plasmacytoma grows only from bone, aura mater or adjacent mucous membrane and cerebral structures are affected secondarily. It is less likely that a solitary cranial plasmacytoma exists, and patients who harbor these neoplasms should undergo complete evaluations to exclude multiple myeloma. Solitary plasmacytoma is radiosensitive and the definite
treatment for the cranial plasmacytoma usually consists of complete surgical resection with adjacent radiation therapy. However, the treatment and prognosis of the cranial plasmacytoma depends on whether this neoplasm is primary or secondary. Most of patients develop cranial plasmacytoma as the presenting form of multiple myeloma and the treatment of in these speical cases is usually unsatisfatory. We report a case of multiple myeloma presented with the motor weakness of both upper and lower
extremities by a bulky cranial plasmacytoma invading cerebrum treated with surgery, radiation therapy and chemotherapy.
Keywords Multiple myeloma, Cranial plasmacytoma
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Korean J Hematol 1999; 34(3): 477-481
Published online September 30, 1999
Copyright © The Korean Society of Hematology.
대뇌를 침범하고 거대 두개형질세포종을 동반한 다발성골수종 1례
김범준, 한지연, 김태균, 이경식, 안재근, 지철, 이강훈, 김현숙
가톨릭대학교 의과대학 내과학교실,
가톨릭대학교 의과대학 신경외과학교실,
가톨릭대학교 의과대학 방사선과학교실
A Case of Multiple Myeloma Presented with a Bulky Cranial Plasmacytoma Invading Cerebrum
Pum Joon Kim, Ji Youn Han, Tae Gyun Kim, Kyung Shick Lee, Jae Gen Ahn, Chul Ji, Kang Hoon Lee, Hyson Sook Kim
Department of Internal Medicine, Neurosurgery, Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Abstract
Although neurologic complications of multiple myeloma are common, brain-involvement is rare, despite the high frequency of the cranial lesions. The cranial plasmacytoma grows only from bone, aura mater or adjacent mucous membrane and cerebral structures are affected secondarily. It is less likely that a solitary cranial plasmacytoma exists, and patients who harbor these neoplasms should undergo complete evaluations to exclude multiple myeloma. Solitary plasmacytoma is radiosensitive and the definite
treatment for the cranial plasmacytoma usually consists of complete surgical resection with adjacent radiation therapy. However, the treatment and prognosis of the cranial plasmacytoma depends on whether this neoplasm is primary or secondary. Most of patients develop cranial plasmacytoma as the presenting form of multiple myeloma and the treatment of in these speical cases is usually unsatisfatory. We report a case of multiple myeloma presented with the motor weakness of both upper and lower
extremities by a bulky cranial plasmacytoma invading cerebrum treated with surgery, radiation therapy and chemotherapy.
Keywords: Multiple myeloma, Cranial plasmacytoma
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