Korean J Hematol 1997; 32(1):
Published online March 31, 1997
© The Korean Society of Hematology
Monoclonal Gammopathy를 동반한 AILD-like T Cell Lymphoma 1례
김병훈, 안명주, 손주현, 이영열, 정태준, 김인순, 최일영, 박일규, 장세진, 박용욱, 이중달
한양대학교 의과대학 내과학교실,
한양대학교 의과대학 임상병리학교실
한양대학교 의과대학 병리학교실
A Case of AILD-like T Cell Lymphoma with Monoclonal Gammopathy
We report a case of 74 year old man presented with generalized lymphadenopathy with hepatosplenomegaly. Lymph node biopsy revealed angioimmunoblastic lymphadenopathy with dysproteinemia(AILD) and most areas of lymph node were
replaced with large atypical lymphocytes which were revealed to be T cells by immunohistochemistry. All together, the patient was diagnosed as AILD-like T cell
lymphoma with bone marrow involvement. The patient presented monoclonal gammopathy(IgG lambda) without any evidence of plasma cell dyscrasia or secondary
amyloidosis. After three cycles of combination chemotherapy including cyclophosphamide, prednisone, vincristine and doxorubicin, the patient achieved partial remission with
decreased level of serum and urine monoclonal protein.
Keywords AILD-like T cell lymphoma; Monoclonal gammopathy;
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Korean J Hematol 1997; 32(1): 146-151
Published online March 31, 1997
Copyright © The Korean Society of Hematology.
Monoclonal Gammopathy를 동반한 AILD-like T Cell Lymphoma 1례
김병훈, 안명주, 손주현, 이영열, 정태준, 김인순, 최일영, 박일규, 장세진, 박용욱, 이중달
한양대학교 의과대학 내과학교실,
한양대학교 의과대학 임상병리학교실
한양대학교 의과대학 병리학교실
A Case of AILD-like T Cell Lymphoma with Monoclonal Gammopathy
Byoung Hun Kim, Myung Ju Ahn, Joo Hyun Son, Young Youl Lee, Tae Jun Jung, In Soon Kim, ll Young Choi, lle Kyu Park, Se Jin Jang, Yong Wook Park, Joong Dal Lee
Department of Internal Medicine, Clinical Pathology, Pathology, Hanyang University College of Medicine, Seoul, Korea
Abstract
We report a case of 74 year old man presented with generalized lymphadenopathy with hepatosplenomegaly. Lymph node biopsy revealed angioimmunoblastic lymphadenopathy with dysproteinemia(AILD) and most areas of lymph node were
replaced with large atypical lymphocytes which were revealed to be T cells by immunohistochemistry. All together, the patient was diagnosed as AILD-like T cell
lymphoma with bone marrow involvement. The patient presented monoclonal gammopathy(IgG lambda) without any evidence of plasma cell dyscrasia or secondary
amyloidosis. After three cycles of combination chemotherapy including cyclophosphamide, prednisone, vincristine and doxorubicin, the patient achieved partial remission with
decreased level of serum and urine monoclonal protein.
Keywords: AILD-like T cell lymphoma, Monoclonal gammopathy,
