Case Report
Korean J Hematol 2009; 44(2):
Published online June 30, 2009
https://doi.org/10.5045/kjh.2009.44.2.117
© The Korean Society of Hematology
폐포단백증 환자에서 발생한 혼합형급성백혈병 1예
정홍렬 이하린 박수범 김효정 이나리아 정재훈 김미라 최영진 정주섭 조군제
부산대학교 의과대학 내과학교실
A Case of Acute Biphenotype Leukemia after Diagnosis of Pulmonary Alveolar Proteinosis
We present the case of a 34-year-old man with acute biphenotype leukemia that co-expressed B-lymphoid and myeloid antigen after the diagnosis of pulmonary alveolar proteinosis (PAP). The diagnosis of PAP was established by Periodic Acid-Schiff reaction staining on the Video Associated Thoracoscope guided lung biopsy and biphenotype leukemia was revealed by immunohistochemical stains of the blasts harvested from the bone marrow biopsy. Supposedly, PAP follows a hematologic malignancy, yet this case shows the reverse sequence. (Korean J Hematol 2009;44:117-121.)
Keywords Pulmonary alveolar proteinosis, Acute biphenotype leukemia, B-lymphoid, Myeloid
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Case Report
Korean J Hematol 2009; 44(2): 117-121
Published online June 30, 2009 https://doi.org/10.5045/kjh.2009.44.2.117
Copyright © The Korean Society of Hematology.
폐포단백증 환자에서 발생한 혼합형급성백혈병 1예
정홍렬 이하린 박수범 김효정 이나리아 정재훈 김미라 최영진 정주섭 조군제
부산대학교 의과대학 내과학교실
A Case of Acute Biphenotype Leukemia after Diagnosis of Pulmonary Alveolar Proteinosis
Hong Ryeol Cheong, Ha rin Lee, Su Bum Park, Hyo Jeong Kim, Na Ri A Lee, Jae Hoon Cheong, Mi Ra Kim, Young Jin Choi, Joo Seop Chung, Goon Jae Cho
Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea
Abstract
We present the case of a 34-year-old man with acute biphenotype leukemia that co-expressed B-lymphoid and myeloid antigen after the diagnosis of pulmonary alveolar proteinosis (PAP). The diagnosis of PAP was established by Periodic Acid-Schiff reaction staining on the Video Associated Thoracoscope guided lung biopsy and biphenotype leukemia was revealed by immunohistochemical stains of the blasts harvested from the bone marrow biopsy. Supposedly, PAP follows a hematologic malignancy, yet this case shows the reverse sequence. (Korean J Hematol 2009;44:117-121.)
Keywords: Pulmonary alveolar proteinosis, Acute biphenotype leukemia, B-lymphoid, Myeloid
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