Case Report

Korean J Hematol 2008; 43(4):

Published online December 31, 2008

https://doi.org/10.5045/kjh.2008.43.4.272

© The Korean Society of Hematology

급성적백혈병에서 발생한 뇌실질의 과립세포육종 1예

정재훈 권보란 김미라 송무곤 설영미 최영진 신호진 정주섭 조군제

부산대학교 의과대학 내과학교실

A Case of Granulocytic Sarcoma in the Brain of a Patient with Acute Erythroleukemia

Jae Hoon Cheong, Bo ran Kwon, Mi ra Kim, Mu gon Song, Young mi Seol, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Goon Jae Cho

Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea

Abstract

Granulocytic sarcoma is a localized tumor that's composed of immature granulocytic cells and this is more common in patient with 8;21 translocation. We present here a case in a 64-year-old man who was diagnosed with acute myelogenous leukemia (erythroleukemia) that had a complex hyperdiploid karyotype. While he underwent chemotherapy, he developed nausea, vomiting, headache and dysarthria. After several diagnostic work-ups, granulocytic sarcoma in the cerebellum and leptomeningeal metastasis of his leukemia were found on the magnetic resonance imaging and the cerebrospinal fluid cytology.

Keywords Leukemia, Erythroblastic, Acute, Sarcoma, Myeloid, Brain

Article

Case Report

Korean J Hematol 2008; 43(4): 272-275

Published online December 31, 2008 https://doi.org/10.5045/kjh.2008.43.4.272

Copyright © The Korean Society of Hematology.

급성적백혈병에서 발생한 뇌실질의 과립세포육종 1예

정재훈 권보란 김미라 송무곤 설영미 최영진 신호진 정주섭 조군제

부산대학교 의과대학 내과학교실

A Case of Granulocytic Sarcoma in the Brain of a Patient with Acute Erythroleukemia

Jae Hoon Cheong, Bo ran Kwon, Mi ra Kim, Mu gon Song, Young mi Seol, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Goon Jae Cho

Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea

Abstract

Granulocytic sarcoma is a localized tumor that's composed of immature granulocytic cells and this is more common in patient with 8;21 translocation. We present here a case in a 64-year-old man who was diagnosed with acute myelogenous leukemia (erythroleukemia) that had a complex hyperdiploid karyotype. While he underwent chemotherapy, he developed nausea, vomiting, headache and dysarthria. After several diagnostic work-ups, granulocytic sarcoma in the cerebellum and leptomeningeal metastasis of his leukemia were found on the magnetic resonance imaging and the cerebrospinal fluid cytology.

Keywords: Leukemia, Erythroblastic, Acute, Sarcoma, Myeloid, Brain

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