Summary of the characteristics of the subjects.
Group 1 (NAT), N=17 (16%) |
Group 2 (Non-NAT), N=91 (84%) |
|
---|---|---|
Gender | ||
Male | 17 (100%) | 88 (97%) |
Female | 0 (0%) | 3 (3%) |
Age | ||
<2 years old | 0 (0%) | 0 (0%) |
2–15 years old | 14 (82%) | 72 (79%) |
≥16 years old | 3 (18%) | 19 (21%) |
Diagnosis | ||
Hemophilia A | 12 (71%) | 68 (75%) |
Hemophilia B | 5 (29%) | 22 (24%) |
Von Willebrand | 0 (0%) | 1 (1%) |
Severity | ||
Severe hemophilia | 11 (65%) | 54 (59%) |
Moderate hemophilia | 6 (35%) | 30 (33%) |
Mild hemophilia | 0 (0%) | 6 (7%) |
VWD type 1 | 0 (0%) | 1 (1%) |
Inhibitor FVIII | ||
Low titer | 0 (0%) | 1 (1%) |
High titer | 0 (0%) | 3 (3.3%) |
Negative | 16 (94%) | 85 (93.4%) |
History of inhibitor | 1 (6%) | 2 (2.2%) |
Number of bagsa) during transfusion | ||
1–4 bags | 9 (53%) | 42 (46%) |
5–10 bags | 6 (35%) | 36 (40%) |
>10 bags (volume of each bag ±50–180 mL) | 2 (12%) | 13 (14%) |
Age of first transfusion | ||
<2 years old | 6 (35%) | 34 (37%) |
2–15 years old | 11 (65%) | 57 (63%) |
≥16 years old | 0 (0%) | 0 (0%) |
Major surgery | ||
Yes | 0 (0%) | 18 (20%) |
No | 17 (100%) | 73 (80%) |
a)Any type of blood component product.
Abbreviations: NAT, nucleic acid testing; VWD, Von Willebrand disease.