Blood Research

Summary of prospective and retrospective studies of treatment with novel agents for primary plasma cells leukemia.

References Study design Patients, N Median age, yr (range) ORR/CR (%) ASCT,
N
Median PFS (mo) Median OS (mo)
Musto et al. [24] Prospective 23 60 (44–80) 73.9/13 9 14 28
Royer et al. [23] Prospective 39 57 (27–71) 69/10 25 15.1 36.3
Nandakumar et al. [25] Retrospective 68 62 (34–91) 90/47 20 13 23
Dhakal et al. [30] Retrospective 277 60 (25–77) 87/19 277 17% at 4 yr 28% at 4 yr
Mina et al. [31] Retrospective 38 58 (34–80) 82/18 28 20 33
Gowda et al. [32] Retrospective 23 56 (42–71) 65/13 23 5.5 18.1
D’Arena et al. [22] Retrospective 29 62 (42–82) 79/28 12 40% at 2 yr 55% at 2 yr
Blood Res 2022;57:S62~S66 https://doi.org/10.5045/br.2022.2022033
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