Adverse events (N=57).
Events | All grades, N (%) | Grade 3/4, N (%) |
---|---|---|
Hematologic | ||
Anemia | 48 (84.2) | 24 (42.1) |
Thrombocytopenia | 22 (38.6) | 10 (17.5) |
Nonhematologic | ||
Fatigue | 6 (10.5) | 0 |
Pneumonia | 6 (10.5) | 2 (3.5) |
Elevated liver transaminases | 6 (10.5) | 0 |
Herpes zoster | 2 (3.5) | 0 |
Muscle spasms | 2 (3.5) | 1 (1.7) |
Pulmonary embolism | 2 (3.5) | 1 (1.7) |
Headache | 1 (1.7) | 0 |
Diarrhea | 1 (1.7) | 0 |
Urinary tract infection | 1 (1.7) | 0 |
Hepatitis B reactivation | 1 (1.7) | 0 |
Peripheral polyneuropathy | 1 (1.7) | 0 |
Cataract | 1 (1.7) | 0 |
Proteinuria | 1 (1.7) | 0 |
Creatinin elevated | 1 (1.7) | 0 |
Pancreas adenocarcinoma | 1 (1.7) | 0 |
Squamous cell carcinoma | 1 (1.7) | 0 |
Neuroendocrine tumor metastasis | 1 (1.7) | 0 |
Low grade dysplasia tubuler adenoma | 1 (1.7) | 0 |