Laboratory findings during the diagnostic approach.
| Laboratory feature | Overall (N=330) | PV (N=61) | OSA (N=96) | CLD (N=31) | |
|---|---|---|---|---|---|
| Hemoglobin (g/dL) | 19.0 (18.1, 20.0) | 19.0 (17.7, 20.6) | 19.5 (18.4, 20.6) | 19.2 (18.0, 20.3) | 0.5 |
| Hematocrit (%) | 56 (54, 61) | 59 (54, 63) | 58 (55, 63) | 58 (53, 63) | >0.9 |
| Mean corpuscular volume (fL) (NA=2) | 90 (86, 93) | 87 (80, 91) | 91 (87, 94) | 91 (87, 95) | 0.2 |
| Mean corpuscular hemoglobin (pg) (NA=2) | 30.4 (28.5, 31.7) | 28.7 (26.2, 30.6) | 30.5 (28.8, 31.9) | 30.6 (29.0, 31.5) | 0.003 |
| Leukocyte count (×109L) | 7.3 (6.2, 9.1) | 10.2 (8.4, 13.9) | 7.0 (6.0, 8.5) | 7.4 (6.2, 9.0) | <0.001 |
| Platelet count (×109L) | 200 (157, 264) | 398 (236, 628) | 182 (143, 220) | 166 (140, 205) | <0.001 |
| EPO (mU/mL) (NA=70) | 10 (6, 16) | 2 (1, 6) | 13 (9, 18) | 16 (9, 36) | 0.002 |
| Low EPO | 43 (16%) | 37 (63%) | 2 (2.9%) | 0 (0%) | |
| High EPO | 61 (23%) | 3 (5.1%) | 25 (36%) | 9 (50%) | |
| pO2 (mmHg) (NA=51) | 66 (57, 73) | 68 (58, 71) | 60 (54, 70) | 51 (47, 61) | <0.001 |
| SaO2 (%) (NA=51) | 93.2 (89.3, 95.0) | 93.4 (89.8, 95.0) | 91.9 (86.2, 94.3) | 83.7 (80.1, 91.8) | <0.001 |
| p50 (NA=168) | 27.0 (25.9, 28.1) | 27.0 (26.1, 27.8) | 27.3 (26.0, 28.1) | 27.6 (26.1, 29.1) | 0.8 |
| Abnormal liver function test (NA=4) | 41 (13%) | 9 (15%) | 13 (14%) | 4 (13%) | >0.9 |
| Elevated LDH (NA=152) | 60 (34%) | 29 (57%) | 10 (21%) | 7 (41%) | 0.002 |
| Glomerular filtration rate (mL/min/1.73 m2) (NA=1) | 93 (77, 108) | 82 (64, 102) | 98 (82, 113) | 95 (83, 104) | 0.003 |
| Iron deficiency (NA=167) | 41 (25%) | 22 (43%) | 8 (17%) | 2 (17%) | 0.009 |
Summaries presented in median (IQR) or N (%).
Abbreviations: CLD, chronic lung disease; EPO, erythropoietin; LDH, lactate dehydrogenase; NA, not available; OSA, obstructive sleep apnea; PV, polycythemia vera.
Blood Res 2021;56:166~174 https://doi.org/10.5045/br.2021.2021111
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