Table 5

Other surgeries and used amount of CFCs.

	Mean age (yr)	Severity (N of cases)	N of case	Hospitalized day	Amount of CFCs per kg (IU/kg)
	Mean age (yr)	Severity (N of cases)	N of case	Hospitalized day	Total	First 3ds	After 3ds
Major operation
Appendectomy	16	S 1	1	4	314.3	208.3	124
Splenectomy	23	S 1	1	31	231.9	139.1	139
Craniotomy & closed drainage	38.75±12.1	S 4	4	67.5±53.9	1069.9±507.4	337±87.1	371.5±153.0
Adenoidectomy	3	S 1	1	6	712.5	437.5	393
Tooth extraction (>3)	47.7±1.2	M 3	3	3.7±0.6	178.1±48.7	178.1±48.7	-
Major operation total/average	34.5±16.7	S 7	10	32.2±24.3	578.9±487.1	217.3±143.3	271.4±166.8
Major operation total/average	34.5±16.7	M 3	10	32.2±24.3	578.9±487.1	217.3±143.3	271.4±166.8
Minor operation
Hemorrhoidectomy	25.6±4.6	S 3	3	4	288.3±89.0	196.9±8.9	78
Removal of lipoma	39	M 1	1	6	120	60	60
Tooth extraction (≤2)	23.0±14.7	S 1	3	1.3±0.6	68.6±33.4	68.6±33.4	-
Tooth extraction (≤2)	23.0±14.7	M 2		1.3±0.6	68.6±33.4	68.6±33.4	-
Tympanoplasty	44	S 1	1	13	73.8	73.8	-
Colonoscopic resection or Bx	25.7±7.6	M 3	3	3.3±1.2	182.1±38.6	182.1±38.6	-
Minor operation total/average	31.6±11.5	S 5	11	4.5±3.5	179.0±112.8	137.6±66.8	98.0±28.3
Minor operation total/average	31.6±11.5	M 6
P^a)	0.09			0.04	0.000	0.005	0.198

^a)P-value less than 0.05 is regarded as statistically significant in comparison with major and minor operation.

Abbreviations: M, moderate hemophilia A; S, severe hemophilia A.