Table 4

Orthopedic surgeries and used amount of CFCs.

	Mean age (yr)	Severity (N of cases)	N of case	Hospitalized days (day)	Amount of CFCs per kg (IU/kg)
	Mean age (yr)	Severity (N of cases)	N of case	Hospitalized days (day)	Total	First 3ds	After 3ds
Major operation
ORIF	30±8.2	S 1	3	34.7±15.8	359.2±110.2	123.8±41.2	123.6±20.8
ORIF	30±8.2	M 2
Synovectomy	20.4±13.3	S 4	7	17.4±10.2	979.5±519.5	267.7±140.8	211.1±95.1
Synovectomy	20.4±13.3	M 3
Spinal stenosis operation	68	S 1	1	50	1,040	325	150
Open fracture operation	28.5±12.2	S 2	4	20.25±5.4	601.6±116.6	222.7±138.5	140±22.8
Open fracture operation	28.5±12.2	M 2					140±22.8
Major operation	27.7±15.9	S 8	15	23.8±14.9	758.7±733.3	209.2±131.7	174.1±74.7
Major operation	27.7±15.9	M 7
Minor operation
Endoscopic synovectomy	19±17.3	S 2	3	4.3±3.2	165.7±59.5	69.6±24.2	78
Endoscopic synovectomy	19±17.3	M 1
Closed fracture operation	7.3±2.3	S 3	3	3.3±0.6	123.4±537	121.3±53.8	-
Minor operation total/average	13.2±12.8	S 5	6	5.8±4.9	143.5±56.2	95.5±46.9	78
Minor operation total/average	13.2±12.8	M 1
P^a)	0.48			0.018	0.040	0.020	0.527

^a)P-value less than 0.05 is regarded as statistically significant in comparison with major and minor operation.

Abbreviations: M, moderate hemophilia A; ORIF, open reduction and internal fixation; S, severe hemophilia A.