Table 2

Univariate and multivariate analysis of prognostic factors for survival in 157 patients with limited natural killer/T cell lymphoma, nasal type.

	Progression-free survival			Overall survival
	Univariate	Multivariate		Univariate	Multivariate
	P	HR (95% CI)	P	P	HR (95% CI)	P
Male sex	0.059	-	-	0.458	-	-
B symptoms	0.568	-	-	0.504	-	-
Age≥60 yr	0.015	0.928 (0.514–1.675)	0.804	0.011	0.943 (0.485–1.835)	0.863
Stage II	0.007	0.965 (0.466–1.999)	0.924	0.076	-	-
LDH>normal	<0.001	2.948 (1.606–5.404)	<0.001	0.009	2.619 (1.394–4.822)	0.003
ECOG PS≥grade 2	0.003	1.778 (0.959–3.288)	0.068	0.016	2.002 (0.991–4.043)	0.053
High Ki-67≥70	0.007	1.388 (0.769–2.507)	0.276	0.068	-	-
low SUV_max<7.1	<0.001	0.538 (0.258–1.126)	0.100	0.056	-	-
Regional LN involvement	0.034	0.627 (0.304–1.290)	0.205	0.386	-	-
Short distance_max	<0.001	0.170 (0.071–0.410)	<0.001	<0.001	0.142 (0.050–0.402)	<0.001
Bilateral LN involvement	<0.001	1.748 (0.980–3.112)	0.059	0.003	2.532 (0.984–4.713)	0.212
Bulky disease (≥7.5 cm)	0531	-	-	0.355	-	-
CTx combined with RTx	<0.001	0.168 (0.079–0.380)	<0.001	<0.001	0.193 (0.087–0.429)	<0.001

Abbreviations: CI, confidence interval; CTx, chemotherapy; distance_max, maximum distance length; ECOG, Eastern Cooperative Oncology Group performance status; HR, hazard ratio; IPI, International Prognostic index; RLN, regional lymph node; RTx, radiotherapy; SUV_max, maximum standard uptake value.

Blood Res 2021;56:72~78 https://doi.org/10.5045/br.2021.2020328