Blood Research

Features of four cases of polycythemia vera emerging while in long-term remission from acute myeloid leukemia.

Case reference Age at AML diagnosis Sex AML type AML treatment Time to PV from AML diagnosis JAK2 V617F at AML diagnosis JAK2 V617F VAF atPV diagnosis
Antonioli et al. [1] 60 M M2 Flu/AraC/Ida ×1
Ida/Etop ×1
AutoSCT
7 yr Not detected 28%
Belotti et al. [5] 71 M M4 AraC/Ida/Etop ×1
Ida/AraC ×2
AraC ×2
7 yr Not done Positive
Portell et al. [6] 59 F M2 Ida/AraC ×1
AraC ×3
5 yr 2% 91%
This case 64 F M1 AraC/Daun ×8
Flu/AraC/Ida ×2
18 yr Not detected 17%

Abbreviations: AML, acute myeloid leukemia; AraC, cytarabine; AutoSCT, autologous stem cell transplantation; Daun, daunorubicin; Etop, etoposide; Flu, fludarabine; Ida, idarubicin; M1, acute myeloid leukemia with minimal maturation; M2, acute differentiated myeloid leukemia; M4, acute myelomonocytic leukemia; VAF, variant allele frequency.

Blood Res 2021;56:121~123 https://doi.org/10.5045/br.2021.2021040
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