Features of four cases of polycythemia vera emerging while in long-term remission from acute myeloid leukemia.
Case reference | Age at AML diagnosis | Sex | AML type | AML treatment | Time to PV from AML diagnosis | ||
---|---|---|---|---|---|---|---|
Antonioli |
60 | M | M2 | Flu/AraC/Ida ×1 Ida/Etop ×1 AutoSCT |
7 yr | Not detected | 28% |
Belotti |
71 | M | M4 | AraC/Ida/Etop ×1 Ida/AraC ×2 AraC ×2 |
7 yr | Not done | Positive |
Portell |
59 | F | M2 | Ida/AraC ×1 AraC ×3 |
5 yr | 2% | 91% |
This case | 64 | F | M1 | AraC/Daun ×8 Flu/AraC/Ida ×2 |
18 yr | Not detected | 17% |
Abbreviations: AML, acute myeloid leukemia; AraC, cytarabine; AutoSCT, autologous stem cell transplantation; Daun, daunorubicin; Etop, etoposide; Flu, fludarabine; Ida, idarubicin; M1, acute myeloid leukemia with minimal maturation; M2, acute differentiated myeloid leukemia; M4, acute myelomonocytic leukemia; VAF, variant allele frequency.