Diagnostic criteria for myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U) [5].
Myeloid neoplasm with mixed myeloproliferative and myelodysplastic features at onset, not meeting the WHO criteria for any other myelodysplastic/myeloproliferative neoplasm, myelodysplastic syndrome, or myeloproliferative neoplasm - <20% blasts in the peripheral blood and bone marrow |
- Clinical and morphological features of one of the categories of myelodysplastic syndromea) |
- Clinical and morphological myeloproliferative features manifesting as a platelet count of ≥450×109/L associated with bone marrow megakaryocytic proliferation and/or a white blood cell count of ≥13×109/La) |
- No history of recent cytotoxic or growth factor therapy that could explain the myelodysplastic/myeloproliferative features |
- No |
a)Cases that meet the criteria for myelodysplastic syndrome with isolated del(5q) are excluded irrespective of the presence of thrombocytosis or leukocytosis.