Blood Research

Diagnostic criteria for myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U) [5].

Myeloid neoplasm with mixed myeloproliferative and myelodysplastic features at onset, not meeting the WHO criteria for any other myelodysplastic/myeloproliferative neoplasm, myelodysplastic syndrome, or myeloproliferative neoplasm - <20% blasts in the peripheral blood and bone marrow
- Clinical and morphological features of one of the categories of myelodysplastic syndromea)
- Clinical and morphological myeloproliferative features manifesting as a platelet count of ≥450×109/L associated with bone marrow megakaryocytic proliferation and/or a white blood cell count of ≥13×109/La)
- No history of recent cytotoxic or growth factor therapy that could explain the myelodysplastic/myeloproliferative features
- No PDGFRA, PDGFRB, or FGFR1 rearrangement and no PCM1-JAK2

a)Cases that meet the criteria for myelodysplastic syndrome with isolated del(5q) are excluded irrespective of the presence of thrombocytosis or leukocytosis.

Blood Res 2021;56:S51~S64 https://doi.org/10.5045/br.2021.2021010
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