Diagnostic workup to differentiate hemophagocytic lymphohistiocytosis from other diseases.
| Differential diagnosis | Tests |
|---|---|
| Malignancy | Bone marrow aspiration/biopsy |
| Neck/chest/abdominopelvic computed tomography | |
| Tumor markers | |
| Infection | Cytomegalovirus, Epstein–Barr virus, parvovirus |
| Hepatitis A, B, C virus | |
| Human immunodeficiency virus | |
| Immunoglobulin E | |
| Parasite-specific antibody | |
| Rheumatic disorder | Fluorescence anti-nuclear antibodyanti-double-strand DNA |
| C3/C4 | |
| Erythrocyte sediment rate | |
| Lupus anticoagulant |
Blood Res 2021;56:S17~S25 https://doi.org/10.5045/br.2021.2020323
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