Frequency and spectra of chromosomal aberrations according to the type of all acute leukemia patients using the multiplex RT-PCR system.
| Chromosomal aberration using multiplex RT-PCR system | Fusion transcript | AML | ALL | MPAL | Total |
|---|---|---|---|---|---|
| t(15;17)(q24;q21) | 67 | 67 | |||
| t(9;22)(q34;q11) | 9 | 34 | 4 | 47 | |
| t(8;21)(q22;q22) | 34 | 34 | |||
| 11q23 | |||||
| t(4;11)(q21;q23) | 3 | 3 | |||
| t(6;11)(q27;q23) | 5 | 5 | |||
| t(11;19)(q23;p13.3) | 2 | 2 | |||
| t(9;11)(p22;q23) | 8 | 1 | 9 | ||
| t(10;11)(p12;q23) | 5 | 1 | 6 | ||
| t(11;19)(q23;p13.3) | 1 | 1 | |||
| t(12;21)(p13;q22) | 15 | 15 | |||
| t(1;19)(q23;p13) | 5 | 5 | |||
| inv(16)(p13;q22) | 23 | 23 | |||
| t(9;9)(q34;q34) | 1 | 1 | 2 | ||
| del(1p32) | 4 | 4 | |||
| t(16;21)(p11;q22) | 3 | 3 | |||
| t(6;9)(p23;q34) | 2 | 2 | |||
| N of positive cases | 159 | 64 | 5 | 228 | |
| Total cases | 521 | 187 | 9 | 717 | |
| NT | 61 | 19 | 0 | 80 | |
| Cases excluding ‘NT’ | 460 | 168 | 9 | 637 | |
| Positive cases excluding ‘NT’ (%) | 35 | 38 | 56 | 36 | |
Abbreviations: ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; MPAL, mixed-phenotype acute leukemia; NT, not tested.
Blood Res 2020;55:225~245 https://doi.org/10.5045/br.2020.2020255
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