Summary of case reports on NF1 and MM.
Case No. | Age/sex | Diagnosis | NF type | Interval from NF1 |
Cytogenetic | Therapy | Outcome | Ref. |
---|---|---|---|---|---|---|---|---|
1 | 59/M | MM IgG-Kappa | 1 | ND | Del 13q, tris 9 and 15 | VTD+auto-sct | VGPR | Accardi |
2 | 76/M | SMM IgG-Kappa | 1 | ND | ND | Follow-up | Accardi |
|
3 | 69/F | MM IgG-Kappa | 1 | 40 yr | Del 13q | VTD | sCR | Our case |
4 | 63/M | MM light chain disease, Lambda | 1 | ND | (1q+), 8q+, 13q+,i (17q), i (18q), and +M. | ND | ND | Zengin |
Abbreviations: auto-sct, autologous stem cell transplantation; MM, multiple myeloma; ND, not detectable; Ref, references; sCR, stringent complete response; VGPR, very good partial response; VTD, bortezomib, thalidomide and dexamethasone.