Fig. 1. Computed tomography (CT) findings at relapse showing splenomegaly (A). CT after 2 courses of romidepsin showing that the splenomegaly improved (B). Peripheral blood smear with May–Giemsa staining (C) and histopathological findings from bone marrow biopsy showing diffuse proliferation of medium-sized lymphoid cells (hematoxylin-eosin staining, ×20) (D), indicating a leukemic-phase peripheral T-cell lymphoma. Immunohistochemical staining expressed (E) CD3, (F) CD4 (weakly), and (G) CD8 lymphocytes.

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