Drug use evaluation of opioid analgesics.
Evaluation items | Appropriate | Inappropriate | |||
---|---|---|---|---|---|
Criteria | N (%) | Criteria | N (%) | ||
Initial drug selection | SA opioid analgesics | 113 (95.0) | LA opioid analgesics | 6 (5.0)a) | |
Initial dose selection | Recommended dosageb) | 91 (80.5) | Higher dosagec) | 22 (19.5) | |
Dosage adjustment | Same dose with reduced pain | 97 (86.6) | Suboptimal dosage increasee) | 5 (4.5) | |
Sufficient dosage increased) | 10 (8.9) | ||||
Dosage conversion | 50–100% of TDD | 83 (85.6) | >100% of TDD | 14 (14.4) |
a)All 6 were autologous hematopoietic stem cell transplantation cases. b)5–15 mg oral short-acting morphine sulfate or equivalent. c)Exceeding 15 mg oral short-acting morphine sulfate or equivalent. d)Increased to 50–100% initial dosage. e)Increased to <50% initial dosage.
Abbreviations: LA, long-acting; SA, short-acting; TDD, total daily opioid dose.